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ProteomicsLong-lived proteins and DNA as candidate predictive biomarkers for tissue associated diseases
Protein turnover, the result of protein synthesis and degradation, is an important mechanism to preserve cellular integrity. The majority of cellular proteins are broken down over a period of hours to weeks to prevent a buildup of proteins that lose their function due to damage caused by misfolding,...
ORGANISM(S): Mus Musculus 
2024-03-21 | PXD050843 |
ProteomicsBrain proteome of honeybee (Apis mellifera)
This project analysis brain proteome of honeybee (Apis mellifera). We aim to find out how gut microbiota affect brain functions.
ORGANISM(S): Apis Mellifera 
2020-11-02 | PXD022304 |
ProteomicsTransketolase promotes MAFLD by limiting inosine-induced mitochondrial activity (Proteomics)
Metabolic dysfunction-associated fatty liver disease (MAFLD) has a global prevalence of about 25% and no approved therapy. Using metabolomic and proteomic analyses, we identified high expression of hepatic transketolase (TKT), a metabolic enzyme of the pentose phosphate pathway, in human and mouse M...
ORGANISM(S): Homo Sapiens 
2024-02-26 | PXD050130 |
ProteomicsProteomics of the Gastric cancer Response to anti-PD1 therapy
To validate the correlation between Th1/Th2 ratio and immunotherapeutic effectiveness, we collected a group of GC patients treated with anti-PD1 therapy, including 7 responder cases (PR) and 7 non-responder cases (SD/PD). The formalin-fixed paraffin-embedded (FFPE) tumor tissue sections derived from...
ORGANISM(S): Homo Sapiens 
2022-11-17 | PXD038188 |
ProteomicsMultilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer
We report a comprehensive proteomic analysis of diffuse-type gastric cancer (DGC) (n=83), intestinal-type gastric cancer (IGC) (n=102), mixed-type gastric cancer (MGC) (n=11), and paired normal adjacent tissues (NATs), including data obtained by proteomics, phospho-proteomics profiling and TFs activ...
ORGANISM(S): Homo Sapiens 
2022-11-18 | PXD038214 |
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