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TranscriptomicsThe Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends
Chromosomal double-strand breaks (DSBs) are resected by 5M-bM-^@M-^Y-nucleases to form 3M-bM-^@M-^Y single-strand DNA (ssDNA) substrates for binding by homologous recombination and DNA damage checkpoint proteins. Two redundant pathways of extensive resection were described both in cells and in vitro...
ORGANISM(S): Saccharomyces cerevisiae 
2012-10-04 | E-GEOD-38601 | biostudies-arrayexpress
ProteomicsIdentification of FgPacC interactor
Identification of Transcription factor FgPacC Interacting Protein by LC-MSMS
ORGANISM(S): Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) (Wheat head blight fungus) (Fusarium graminearum) 
2022-08-11 | PXD029059 | Pride
Fusarium graminearum lc-msms 
TranscriptomicsTranscriptome profiling of Bacillus subtilis OKB105 in response to rice seedlings
Plant growth-promoting rhizobacteria (PGPR) are soil beneficial microorganisms that colonize plant roots for nutritional purposes and accordingly benefit plants by increasing plant growth or reducing disease. But it still remains unclear which mechanisms or pathways are involved in the interactions ...
ORGANISM(S): Bacillus subtilis 
2014-10-17 | E-GEOD-62421 | biostudies-arrayexpress
TranscriptomicsPulmonary alveolar macrophages (PAMs) of Tongcheng piglets response to HP-PRRSV infection in vivo
Porcine reproductive and respiratory syndrome (PRRS), caused by PRRS virus (PRRSV), is the most economically important disease in pig populations. Lung damage is one major pathological condition following PRRSV infection, often leading to animal death. In vivo, PRRSV productive infection occurs pred...
ORGANISM(S): Sus scrofa 
2012-06-30 | E-GEOD-22782 | biostudies-arrayexpress
ProteomicsTargeting mitochondria-inflammation circuit by β-hydroxybutyrate mitigates heart failure with preserved ejection fraction
Rationale: Over 50% of heart failure patients have preserved, rather than reduced ejection fraction (HFpEF vs. HFrEF). Complexity of its pathophysiology and the lack of animal models hamper the development of effective therapy for HFpEF. Objective: This study was designed to investigate the metabol...
ORGANISM(S): Mus Musculus 
2021-10-22 | PXD021957 |
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