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Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
In this study, we leveraged 15 paired plasma samples collected from the same individuals who exhibited rapid progression from DM to DR within 1-2 years and conducted integrated proteomic and metabolomic analyses to investigate molecular changes associated with disease progression. Key proteins were ...
ORGANISM(S): Homo Sapiens 
2026-05-19 | PXD078538 |
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