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MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownA new species of Phoebe (Lauraceae) from south-western China.
Not available
S-EPMC7066262 | biostudies-literature
UnknownDiscovery of a potent, covalent BTK inhibitor for B-cell lymphoma.
Not available
S-EPMC4027949 | biostudies-literature
UnknownChinese expert consensus on Bruton tyrosine kinase inhibitors in the treatment of B-cell malignancies.
Not available
S-EPMC10578030 | biostudies-literature
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
UnknownCyrtomiumadenotrichum (Dryopteridaceae), a new species from Guangxi, China.
Not available
S-EPMC11220402 | biostudies-literature
MetabolomicsImaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori

The complex stripes and patterns of insects play key roles in behavior and ecology. However, the fine-scale regulation mechanisms underlying pigment formation and morphological divergence remain largely unelucidated. Here we demonstrated that imaginal disc growth factor (IDGF) maintains cuticle s...

2020-09-20 | MTBLS1825 | MetaboLights
GenomicsBase-resolution methylation patterns accurately predict transcription factor bindings in vivo
Detecting in vivo transcription factor (TF) binding is important for understanding gene regulatory circuitries. ChIP-seq is a powerful technique to empirically define TF binding in vivo. However, the multitude of distinct TFs makes genome-wide profiling for them all labor-intensive and costly. Algor...
ORGANISM(S): Mus musculus 
2015-03-02 | E-GEOD-65093 | biostudies-arrayexpress
GenomicsGlobal Reorganization of Chromatin Architecture during Embronic Stem Cell Differentiation
The 3D organization of the genome is important for regulation of diverse nuclear processes ranging from transcription to DNA replication. Knowledge of the higher order chromatin structure is critical for understanding mechanisms of gene regulation by long-range control elements such as enhancers and...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-52457 | biostudies-arrayexpress
UnknownGender differences in depressive symptoms among Chinese older adults based on fairlie decomposition analysis
Not available
S-EPMC10637998 | biostudies-literature
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