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ProteomicsExpression of a surfactant protein C mutation impairs postnatal expansion of alveolar type 2 epithelial cells leading to permanent cell loss and decreased repair capacity in adult lungs
Mutations in the gene encoding surfactant protein C (SFTPC) are associated with interstitial lung disease in children and adults. To assess the natural history of disease, we knocked-in a familial, disease-associated SFTPC mutation, L188Q (L184Q in mice), into the mouse Sftpc locus. Expression of th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-08-19 | MSV000085976 | MassIVE
MetabolomicsStage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis

OBJECTIVE: Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA.

METHODS: We investi...

2023-01-31 | MTBLS5297 | MetaboLights
UnknownRegional environmental differences significantly affect the genetic structure and genetic differentiation of Carpinus tientaiensis Cheng, an endemic and extremely endangered species from China.
Not available
S-EPMC10885731 | biostudies-literature
UnknownDual roles of c-Myc in the regulation of hTERT gene.
Not available
S-EPMC4176324 | biostudies-literature
UnknownDiscovery of Novel Resistance Mechanisms of Vibrio parahaemolyticus Biofilm against Aminoglycoside Antibiotics.
Not available
S-EPMC10135303 | biostudies-literature
UnknownThe association between plant-based diet and erectile dysfunction in Chinese men.
Not available
S-EPMC8117588 | biostudies-literature
UnknownMagnetic versus conventional stent in ureteral stenting: meta-analysis.
Not available
S-EPMC11287378 | biostudies-literature
TranscriptomicsGeneration of neural progenitor cells by chemical cocktails and hypoxia
Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts by a chemical cocktail, namely VCR (V, VPA, an inhibitor of HDACs; C, CHIR99021, an inhibitor of GSK-3 kinases and R, Repsox, an inhibitor o...
ORGANISM(S): Mus musculus 
2015-04-27 | E-GEOD-68311 | biostudies-arrayexpress
MetabolomicsGNPS - MS/MS networking guided analysis of molecule and gene cluster families - Figure 4
Paper Title: MS/MS networking guided analysis of molecule and gene cluster families Author List: Don Duy Nguyen, Cheng-Hsuan Wu, Wilna J. Moree, Anne Lamsa, Marnix H. Medema, Xiling Zhao, Ronnie G. Gavilan, Marystella Aparicio, Librada Atencio, Chanaye Jackson, Javier Ballesteros, Joel Sanchez, Jer...
ORGANISM(S): Pseudoalteromonas Piscicida Jcm 20779t Pseudoalteromonas 04m1a Pseudoalteromonas Ot59 
2014-02-18 | MSV000078551 | GNPS
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
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