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Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
Toxoplasma gondii is an obligate intracellular protozoan parasite that poses a severe threat to human health, especially those immune-compromised individuals. Sulfadiazine sodium (SDZ) is widely used for the treatment of human toxoplasmosis. However, systems biology researches on the therapeutic eff...
2019-06-18 | MTBLS852 | MetaboLights
Pluripotent stem cells can be induced from somatic cells, providing an unlimited cell resource for regenerative medicine. However, genetic manipulation and difficult-to-manufacture strategies used in reprogramming limit their clinical applications. Here, we show pluripotency can be induced from mous...
ORGANISM(S): Mus musculus 

Maintaining the health of seafarers is a difficult task during long-term voyages. Little is known about the corresponding changes in the gut microbiome-host interaction. This study recruited 30 seafarers undertaking a 6-month voyage and analyzed their gut microbiota using 16S rRNA gene sequencing...

2022-09-29 | MTBLS5335 | MetaboLights
To investigate the potential function of miRNAs during male gametogenesis in rice, we first obtained gene expression profiles by using Affymetrix microarray technologies. In genome-scale, we found a common characteristic shared by rice and Arabidopsis, which vast of genes are down regulated from Pb ...
ORGANISM(S): Oryza sativa Indica Group 
To investigate the potential function of miRNAs during male gametogenesis in rice, 13-40 nt RNA were extrected from tricellular pollen (TCP) for high-throughput sequencing. We identified 104 unique miRNAs from TCP library, 57 of which are novel derived from 39 pre-miRNAs. This subseries contain one ...
ORGANISM(S): Oryza sativa Indica Group 
The Pacific white shrimp (Litopenaeus vannamei), one of the most widely cultured shrimp species in the world, usually suffered from chilling stress in China. In order to reveal inner proteomics mechanism of chilling tolerance, we conducted a proteomic analysis on two contrasting shrimp cultivars, na...
ORGANISM(S): Litopenaeus Vannamei 
2018-05-25 | PXD009889 |
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