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MetabolomicsChanges in L-phenylalanine concentration reflect and predict response to anti-PD-1 treatment combined with chemotherapy in patients with non-small cell lung cancer
Chemotherapy combined with checkpoint blockade antibodies targeting programmed cell death protein (PD-1) has achieved remarkable success in non-small cell lung cancer (NSCLC). However, few patients benefit from long-term treatment. Therefore, biomarkers capable of guiding the optimal therapeutic sel...
2025-06-16 | MTBLS11232 | MetaboLights
ProteomicsProteomic Analysis Muscle and Fat Deposition in Muscovy duck
The liver responsible for 90% lipid synthesis in poultry thus plays important role in the growth of Muscovy duck, which obtains high-fat deposition ability in a time-dependent manner. Therefore, male Muscovy ducks at the age of 14, 28, 42, and 56 days were selected for body weight (BW), carcass weig...
ORGANISM(S): Anas Platyrhynchos 
PXD025920 |
ProteomicsPeptidomics and Quantitative Proteomics Analysis of Peptides from Ophiocordyceps sinensis
This project includes two parts of mass spectrometry-based omics analysis. First, peptidomics analysis was performed to identify endogenous free peptides from Ophiocordyceps sinensis. Second, quantitative proteomic analysis was applied to investigate the global protein expression changes in RAW 264....
ORGANISM(S): Mus Musculus 
PXD076647 |
ProteomicsUtilizing Liquid Biopsy-Derived Extracellular Vesicle Protein Biomarkers for Diagnosis and Prognostic Assessment in Lung Squamous Cell Carcinoma
In the context of pulmonary nodules detected in imaging, there is currently a lack of highly effective and non-invasive methods for both diagnosing and prognosticating lung squamous cell carcinoma (LUSC). Therefore, in this study, we explored the potential of plasma-derived extracellular vesicles (E...
ORGANISM(S): Homo Sapiens 
2023-12-18 | PXD047893 |
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