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ProteomicsJMJD2 regulates enhancer-promoter interactions via biocondensate formation
Enhancer-promoter (E-P) interactions regulate transcription for cell fate determination. However, the regulatory mechanisms of E-P interactions remain elusive. Here, a chromatin interaction-based proteomics approach, LoopID, was developed to profile the proteins at certain E-P anchors, which were te...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD069064 | Pride
Enhancer-promoter interactions Proximity ligation Loopid Biocondensates Proteome 
ProteomicsProteomics of the placenta of yak in the early, middle and later stages of pregnancy studies the reproductive physiological mechanism of yak pregnancy, and provides relevant theoretical data for the growth and development of the placenta
The placental histological data of yak in the early, middle and later stages of pregnancy, screening the ways to participate in the regulation of the dynamic development of yak placenta during pregnancy, and exploring the potential function of placental proteins in placenta tissue, in order to provi...
ORGANISM(S): Bos Grunniens 
2023-03-16 | PXD040910 |
ProteomicsThe response mechanism of Cucurbita ficifolia under the FoC stress and the Identification of NBS type disease -resistance genes
For the first time, this study reveal the response of C. ficifolia leaf to FOC infection at the transcriptome and proteome levels, uncovered that FOC infection activates plant hormone signaling, and transcription factors while suppressing wax biosynthetic process and photosynthesis. The results prov...
ORGANISM(S): Cucurbita Ficifolia 
2021-08-24 | PXD028075 |
ProteomicsMulti-Omics Analysis Reveals Alcohol exposure affects Ferroptosis pathway in Brain
Alcohol-related brain damage (ARBD) constitutes a major global public health issue and is often comorbid with neuropsychiatric disorders such as Alzheimer's and Parkinson's diseases. Ferroptosis, a form of regulated cell death characterized by iron dependency and lipid peroxidation, has been implica...
ORGANISM(S): Mus Musculus 
2026-03-11 | PXD075525 |
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