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ProteomicsThe Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome
Stress-inducible molecular chaperones have essential roles in maintaining protein homeostasis, but the extent to which they affect global proteome stability remains unclear. Here, we analyzed the effects of the DnaK (Hsp70) system on protein stability in Escherichia coli using pulse proteolysis comb...
ORGANISM(S): Escherichia coli 
2019-06-24 | PXD012929 | Pride
Protein stability Proteomics Pulse proteolysis Chaperones 
TranscriptomicsExpression data from murine colon tissue after exposure to 4% DSS for 6 days DSS followed by 4 days of water or 1% L-arginine
L-Arginine (L-Arg) is the substrate for both inducible nitric oxide synthase and arginase, which are upregulated in human IBD and in mouse colitis models. We have found that L-Arg supplementation enhances wound restitution in vitro, and improves the clinical parameters of weight loss, survival, and ...
ORGANISM(S): Mus musculus 
2012-06-26 | E-GEOD-34874 | biostudies-arrayexpress
UnknownMetabolomic analysis reveals spermatozoa and seminal plasma differences between Duroc and Liang guang Small-spotted pig.
Not available
S-EPMC9853278 | biostudies-literature
UnknownEffects of urotensin-II on cytokines in early acute liver failure in mice.
Not available
S-EPMC4363753 | biostudies-literature
MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
UnknownMetastasis-associated long noncoding RNAs in gastrointestinal cancer: Implications for novel biomarkers and therapeutic targets.
Not available
S-EPMC5075548 | biostudies-literature
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownPolycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.
Not available
S-EPMC2581563 | biostudies-literature
UnknownFusarium diversity associated with diseased cereals in China, with an updated phylogenomic assessment of the genus.
Not available
S-EPMC10282163 | biostudies-literature
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