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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
UnknownRegulatory Mechanisms of Free Umami Amino Acid Accumulation in Fresh Waxy Kernels: Insights from Transcriptome and Metabolomics Analyses.
Not available
S-EPMC12609758 | biostudies-literature
TranscriptomicsTranscript profiling of Lin-Sca-1+c-Kit+ (LSK) cells from mice reconstituted with wild type and necdin null fetal liver cells following a sublethal dose of irradiation (6,5 Gy)
compare the gene expression profile between irradiated Lin-Sca-1+c-Kit+ (LSK) cells from mouse bone marrow reconstituted with wild type and necdin null fetal liver cells The Affymetrix oligonucleotide array was used for this analysis compare the gene expression profile betweenirradiated Lin-Sca-1+c-...
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-39153 | biostudies-arrayexpress
ProteomicsEffects of arbuscular mycorrhizal fungi on Pteris cretica L var. nervosa fronds antimony enrichment, morphology and proteome changes during antimony phytoremediation
Pteris cretica L var. nervosa is one of the dominent fern species at antimony mining area where arbuscular mycorrhizal fungi can be found as a symbiosis. The effect of AMF on fern exposed to long-term excessive Sb was pooly understood. The project applied this fern co-cultivting with or withour AMF ...
ORGANISM(S): Pteris cretica var. nervosa 
2024-01-19 | PXD012678 | Pride
Arbuscular mycorrhizal fungi Antimony phytoremediation Pteris cretica l var. nervosa Long-term exposure Fronds proteomic identification 
TranscriptomicsTranscription profiling of human hematopoietic stem cells engrafted into fetal goats
Robust human-goat chimerism was achieved by transplanting human CD34+Lin- cord blood cells into fetal goats. We observed a broad distribution of GFP-marked human cells in non-hematopoietic organs including kidney, muscle, lung, and heart of transplant goats. Various marker techniques indicated that...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1801 | biostudies-arrayexpress
ProteomicsZhao_DNADamageFLAGAP_P36_TripleTOF5600
This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 5600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Yichao Zhao. Immunoprecipitation and mass spectrometry acquisition was performed by Zhen...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-15 | MSV000092179 | MassIVE
ProteomicsZhao_DNADamageTurboID_P36_5600
This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 5600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Yichao Zhao. Immunoprecipitation and mass spectrometry acquisition was performed by Zhen...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-06-15 | MSV000092177 | MassIVE
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