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GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
UnknownEscaping but not the inactive X-linked protein complex coding genes may achieve X-chromosome dosage compensation and underlie X chromosome inactivation-related diseases.
Not available
S-EPMC10336589 | biostudies-literature
UnknownUnusual X chromosome inactivation maintenance in female alveolar type 2 cells is correlated with increased numbers of X-linked escape genes and sex-biased gene expression.
Not available
S-EPMC9968984 | biostudies-literature
ProteomicsSelf-anticoagulant sponges for whole blood auto-transfusion and its mechanism of coagulation factor inactivation
Clinical use of intraoperative auto-transfusion requires the removal of platelets and plasma proteins due to the pump-based suction and water-soluble anticoagulant administration, which causes dilutional coagulopathy. Herein, we develop a carboxylated and sulfonated heparin-mimetic polymer-modified ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-23 | PXD044005 | Pride
Anticoagulation  coagulation factor inactivation  whole blood auto-transfusion 
UnknownSynthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Not available
S-EPMC10667340 | biostudies-literature
UnknownDeep learning versus manual measurement of hallux valgus angle and intermetatarsal angle on Weight-Bearing X-rays in hallux valgus.
Not available
S-EPMC12838063 | biostudies-literature
ProteomicsEffects of arbuscular mycorrhizal fungi on Pteris cretica L var. nervosa fronds antimony enrichment, morphology and proteome changes during antimony phytoremediation
Pteris cretica L var. nervosa is one of the dominent fern species at antimony mining area where arbuscular mycorrhizal fungi can be found as a symbiosis. The effect of AMF on fern exposed to long-term excessive Sb was pooly understood. The project applied this fern co-cultivting with or withour AMF ...
ORGANISM(S): Pteris cretica var. nervosa 
2024-01-19 | PXD012678 | Pride
Arbuscular mycorrhizal fungi Antimony phytoremediation Pteris cretica l var. nervosa Long-term exposure Fronds proteomic identification 
TranscriptomicsLncRNAs expression profiles in the livers of 20-month-old male HBx transgenic mice and C57BL/6 wild-type mice
The hepatitis B virus X protein (HBx) has been implicated as an oncogene in both epigenetic modifications and genetic regulation during hepatocarcinogenesis, but the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which regulate gene expression with little or no protein...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-42185 | biostudies-arrayexpress
UnknownEfficacy and Safety of Hou Gu Mi Xi on Spleen Qi Deficiency in Patients with Nonorganic Gastrointestinal Disorders: Protocol for a Multicenter, Randomized, Placebo-Controlled Trial.
Not available
S-EPMC6304527 | biostudies-literature
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