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ProteomicsActivation of dimerized BRS3-EP3 suppresses melanoma cell migration through coupling Gαs protein
The mechanism underlying the crosstalk between Gαq-coupled bombesin receptor subtype-3 (BRS3) and Gαi-coupled E-prostanoid 3 receptor (EP3) remains unknown. Here, we report that BRS3 and EP3 form dimers in the membrane of living HEK-293T cells. Interestingly, we found that BRS3-EP3 dimers switched t...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD042449 | Pride
Bombesin receptor subtype-3 E-prostanoid 3 receptor Cell migration Proteomics G-protein-coupled receptors dimerization 
ProteomicsMultifaceted insights into the environmental adaptability of Arnebia guttata under drought stress
Introduction: Global warming has led to increased environmental stresses on plants, notably drought. This affects plant distribution and species adaptability, with some medicinal plants showing enhanced drought tolerance and increased medicinal components. In this pioneering study, we delve into the...
ORGANISM(S): Arnebia Guttata 
2024-05-31 | PXD052741 |
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