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MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
ProteomicsPlasma proteomic profiling of the SMNTT cohort at multiple time points before and after macronutrient intake
This dataset comprises plasma proteomics data from 24 individuals measured at fasting and at 30, 60, 120, and 180 minutes following the intake of four distinct pure macronutrient loads (glucose, protein, butter, and olive oil).
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062382 | Pride
Human  blood plasma  postprandial 
ProteomicsPlasma proteomic profiling of the MMTT cohort at fasting state
This dataset comprises plasma proteomics data from 147 individuals measured at fasting state.
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062404 | Pride
Human  blood plasma  postprandial 
ProteomicsPlasma proteomic profiling of the MMTT cohort at 60 minutes after the mixed-meal tolerance test
This dataset comprises plasma proteomics data from 147 individuals measured at 60 minutes following the mixed-meal tolerance test
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062431 | Pride
Human  blood plasma  postprandial 
ProteomicsPlasma proteomic profiling of the MMTT cohort at 120 minutes after the mixed-meal tolerance test
This dataset comprises plasma proteomics data from 147 individuals measured at 120 minutes following the mixed-meal tolerance test
ORGANISM(S): Homo sapiens (Human) 
2025-07-29 | PXD062484 | Pride
Human  blood plasma  postprandial 
ProteomicsThe p-MYH9/USP22/HIF-1α axis promotes lenvatinib resistance and cancer stemness in hepatocellular carcinoma
To understand the role of HIF1a in lenvatinib resistance, we conducted label-free quantitative proteome analysis in both control and lenvatinib resistance cell lines. This analysis revealed changes in the proteome due to the lenvatinib resistance, providing a valuable reference for further investiga...
ORGANISM(S): Homo Sapiens 
2024-08-29 | PXD055440 |
ProteomicsMulti-omic analysis reveals a CAF-stemness-governed classification in HCC liver transplant recipients
In patients with hepatocellular carcinoma (HCC) meeting the Milan criteria, liver transplantation (LT) is an effective therapy. This study aims to define the survival-related molecular biological features helping precisely identifying the patients with HCC beyond the Milan criteria who have acceptab...
ORGANISM(S): Homo Sapiens 
2025-02-24 | PXD061119 |
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