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MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
ModelsLiu1999_PulsatileSecretion
This a model from the article: A dynamical model for the pubsatile secretion of the hypothalamo-pituitary-adrenal axis. Yi-wei Liu, Zhi-Hong Hu, Jian-Hua Peng and Bing-Zheng Liu Mathematical and Computer Modelling Volume 29, Issue 4, February 1999, Pag...
2005-01-01 | MODEL1006230060 | BioModels
UnknownSolar-driven defluorination via hydroxyl radical spillover for complete mineralization of organofluorine pollutants without fluoride byproducts.
The recalcitrance of fluorinated organic pollutants-featuring robust Csp²-F and Csp³-F bonds-poses critical challenges to aquatic ecosystems due to their extreme persistence and bioaccumulation. Whereas current destruction strategies suffer from high energy consumption and non-selective, here we pre...
S-EPMC12357893 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsCryo-EM Structures of ALECT2 Filaments from Human Renal Biopsies
The project aims to characterize the state of disulfide bond formation in recombinant LECT2 refolded under non-reducing conditions.
ORGANISM(S): Homo Sapiens 
2026-01-05 | PXD072679 |
UnknownClinical Characteristics of Coronavirus Disease 2019 in China.

Background

Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients.

Methods

We extracted data regarding 1099 patients with laboratory-confirm...
S-EPMC7092819 | biostudies-literature
UnknownDraft genome sequence of Camellia sinensis var. sinensis provides insights into the evolution of the tea genome and tea quality.
Tea, one of the world's most important beverage crops, provides numerous secondary metabolites that account for its rich taste and health benefits. Here we present a high-quality sequence of the genome of tea, Camellia sinensis var. sinensis (CSS), using both Illumina and PacBio sequen...
S-EPMC5939082 | biostudies-literature
UnknownThe tea plant reference genome and improved gene annotation using long-read and paired-end sequencing data.
Tea is a globally consumed non-alcohol beverage with great economic importance. However, lack of the reference genome has largely hampered the utilization of precious tea plant genetic resources towards breeding. To address this issue, we previously generated a high-quality reference genome of tea p...
S-EPMC6629666 | biostudies-literature
UnknownGenotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies.
Genome-wide association studies have identified susceptibility loci for esophageal squamous cell carcinoma (ESCC). We conducted a meta-analysis of all single-nucleotide polymorphisms (SNPs) that showed nominally significant P-values in two previously published genome-wide scans that included a total...
S-EPMC3315211 | biostudies-literature
UnknownThe functional spectrum of low-frequency coding variation.

Background

Rare coding variants constitute an important class of human genetic variation, but are underrepresented in current databases that are based on small population samples. Recent studies show that variants altering amino acid sequence and protein function are enriched at low variant ...
S-EPMC3308047 | biostudies-literature
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