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Proteomicsproteomic analysis reveals the toxin diversity of the spider Macrothele bannaensis
pider toxins are an important and abundant source of bioactive compounds and represent molecular candidates for the development of novel compounds for use in medicine and agriculture. Despite the vast diversity of spider species, only a small fraction of them have been studied in detail regarding ve...
ORGANISM(S): Macrothele 
2025-07-09 | PXD065984 |
ProteomicsProteomic analysis of Rhitymna verruca
Rhitymna verruca is a large nocturnal wandering spider and an important natural predator of agricultural and forestry pests, with its venom playing a key role in prey capture. However, systematic studies on the composition of its venom remain scarce. In this study, we performed an integrated analysi...
ORGANISM(S): Unclassified Sparassidae 
2025-10-29 | PXD070066 |
ProteomicsIntegrated metagenomic and metaproteomic analyses reveal the critical role of bacteria in coral bleaching
Coral reefs worldwide are facing rapid decline due to coral bleaching. However, knowledge of the physiological characteristics and molecular mechanisms of coral symbionts respond to stress is scarce. Here, metagenomic and metaproteomic approach were utilized to shed light on the changes in the compo...
ORGANISM(S): Acropora Muricata 
2023-04-17 | PXD041598 |
ProteomicsCeramide Disrupts TM9SF2-PGK1 Axis to Redirect PD-L1 Trafficking and Enhance Antitumor Immunity
The programmed cell death protein 1 (PD-1) / programmed death-ligand 1 (PD-L1) axis represents a cornerstone of cancer immunotherapy, yet the dynamic shuttling of PD-L1 between endosomal recycling and lysosomal degradation routes limits durable responses. Using a CRISPR screen targeting glycosphingo...
ORGANISM(S): Homo Sapiens 
2026-02-27 | PXD075012 |
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