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TranscriptomicsTranscriptomic analyses of Myc-induced zebrafish liver cancer
To study the characteristics and mechanisms of Myc-induced zebrafish liver tumor, next-generation sequencing-based SAGE analyses were used to examine the transcriptomes of tumor and control samples. The results indicated that ribosome proteins were overwhelmingly up-regulated in the Myc-induced live...
ORGANISM(S): Danio rerio 
2013-04-02 | E-GEOD-40745 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analyses of Kras induced zebrafish liver cancer
The kras transgenic line was generated by using a mifepristone-inducible transgenic system in combination with a Cre-loxP system. Most of the induced transgenic fish developed hepatocellular carcinoma at 6 month-post-induction. Transcriptome profiling of Kras tumor sample (6T1 and 6T2) and control s...
ORGANISM(S): Danio rerio 
2013-12-24 | E-GEOD-53630 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analyses of TCDD treated zebrafish liver
To fully understand molecular toxicity of TCDD in an in vivo animal model, adult zebrafish were exposed to TCDD at 10 nM for 96 h and the livers were sampled for RNA-sequencing based transcriptomic profiling. A total of 1,058 differently expressed genes were identified based on fold-change>2 and TPM...
ORGANISM(S): Danio rerio 
2013-11-12 | E-GEOD-49915 | biostudies-arrayexpress
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