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GenomicsGenome wide association study of leprosy in Chinese population

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

phs000217.v1.p1 | EGA
TranscriptomicsDigital Gene Expression Analysis Based on Integrated De Novo Transcriptome Assembly of Sweet Potato [Ipomoea batatas (L.) Lam.]
More than 3.5 million raw DGE tags were obtained in each library. The clean tags in each sample ranged from 3.35 to 3.63 million, and the distinct clean tags ranged from 93,593 to 139,389. The 21 bp DGE clean tags were mapped to sweet potato transcripts. Then, we compared 7 libraries pair-wisely so ...
ORGANISM(S): Ipomoea batatas 
2012-02-18 | E-GEOD-35929 | biostudies-arrayexpress
UnknownTectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Not available
S-EPMC7489913 | biostudies-literature
TranscriptomicsNasopharyngeal carcinoma patient samples: radio-sensitive samples vs. radio-resistant samples
Expression profiling of nasopharyngeal carcinoma patients comparing radio-sensitive samples with radio-resistant samples. Two condition-experiments, radio-sensitive and radio-resistant nasopharyngeal carcinoma patients. Biological replicates: 8 radio-sensitive, 12 radio-resistant, different donors i...
ORGANISM(S): Homo sapiens 
2013-09-21 | E-GEOD-32389 | biostudies-arrayexpress
UnknownGenomic characteristics and drug screening among organoids derived from non-small cell lung cancer patients.
Not available
S-EPMC7396373 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownLoss of LBP triggers lipid metabolic disorder through H3K27 acetylation-mediated C/EBPβ- SCD activation in non-alcoholic fatty liver disease.
Not available
S-EPMC10839665 | biostudies-literature
UnknownNuclear receptor corepressor 1 represses cardiac hypertrophy.
Not available
S-EPMC6835202 | biostudies-literature
TranscriptomicsA robust single primate neuroepithelial cell clonal expansion system for neural tube development and disease studies
Developing a model of primate neural tube (NT) development is important to promote many NT disorder studies in model organisms. Here, we report a robust and stable system to allow for clonal expansion of single monkey neuroepithelial stem cells (NESCs) to develop into miniature NT-like structures. S...
ORGANISM(S): Macaca mulatta 
2015-11-21 | E-GEOD-73892 | biostudies-arrayexpress
ProteomicsHeat stress triggers nuclear invagination and spatial compartmentalization of protein metabolism
Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the classical heat shock response. However, the subcellular coordination of these stress responses remains poorly understood. In this study, we identify reversi...
ORGANISM(S): Homo Sapiens 
2026-01-23 | PXD073534 |
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