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TranscriptomicsTiled Microarray Identification of Novel Viral Transcript Structures and Distinct Transcriptional Profiles During Two Modes of Productive Murine Gammaherpesvirus 68 Infection.
We applied a custom tiled microarray to examine murine gammaherpesvirus 68 (MHV68) polyadenylated transcript expression in a timecourse of de novo infection of fibroblast cells and following phorbol ester-mediated reactivation from a latently-infected B cell line. During de novo infection, all ORFs ...
ORGANISM(S): Mus musculus 
2012-02-16 | E-GEOD-35866 | biostudies-arrayexpress
TranscriptomicsTiled Array Experiment of Murine Gammaherpesvirus 68 Transcripts In Newly Infected Fibroblasts
Murine NIH3T3 fibroblasts were infected with MHV68 and RNA expression was examined over an 18 hour timecourse experiment. Study includes 8 samples isolated at 0, 2, 4, 6, 8, 10, 12, and 18 hours after infection of NIH3T3 fibroblasts with murine gammaherpesvirus 68 at a multiplicity of infection of 1...
ORGANISM(S): Mus musculus 
2012-02-16 | E-GEOD-35863 | biostudies-arrayexpress
TranscriptomicsTiled Array Experiment of Murine Gammaherpesvirus 68 Transcripts Upon TPA-Stimulated Reactivation From Latency
Murine A20 B cells harboring latent MHV68 were treated with TPA and RNA expression was examined over a 24 hour timecourse experiment. Study includes 4 samples- an untreated sample and reactivation samples isolated at 6, 12, and 24 hours after treatment of a latent MHV68+ B cell line with TPA.
ORGANISM(S): Mus musculus 
2012-02-16 | E-GEOD-35865 | biostudies-arrayexpress
ProteomicsProteomics of EBV-infected lytic and refractory cells
Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...
ORGANISM(S): Homo sapiens (Human) 
2016-04-27 | PXD001838 | Pride
Proteomic analysis Epstein-barr virus Lytic activation 
Proteomics,MultiomicsProteomics of EBV-infected lytic and refractory cells
Most humans are infected with Epstein-Barr virus (EBV), a cancer-causing virus. While EBV generally persists silently in B lymphocytes, periodic lytic (re-)activation of latent virus is central to its life cycle and to most EBV-related diseases. However, a substantial fraction of EBV-infected B cell...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079993 | MassIVE
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