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Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
Translational reprogramming is part of the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress, which acts to the advantage of cancer growth and development in different stress conditions. But the mechanism of ER stress-related translational reprogramming in colorectal carcinoma...
ORGANISM(S): Homo Sapiens 
2022-05-16 | PXD033930 |

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

Structural analysis of the ApoD-CD36 complex by XL-MS.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD070975 |
We isolated PDGFRβ+ mural cells from tumor-adjacent normal human brain, lung, and kidney tissues. After lysis, we used LC-MS to profile differentially expressed proteins across these three cell types.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD071101 |
Liquid chromatography-mass spectrometry (LC-MS) analysis of the anti-ApoD immunoprecipitate.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD071099 |
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