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TranscriptomicsArabidopsis AGO1 and AGO10 bound sRNAs
The shoot apical meristem (SAM) comprises a group of undifferentiated cells that divide to maintain the plant meristem and also give rise to all shoot organs. SAM fate is specified by class III HOMEODOMAIN-LEUCINE ZIPPER (HD-ZIP III) transcription factors, which are targets of miR166/165. In Arabido...
ORGANISM(S): Arabidopsis thaliana 
2012-08-03 | E-GEOD-39885 | biostudies-arrayexpress
MetabolomicsCell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells

Multicellular organisms such as plants contain various cell types with specialized functions. Analyzing the characteristics of each cell type reveals specific cell functions and enhances our understanding of organization and function at the organismal level. Guard cells (GCs) are specialized epid...

2024-09-03 | MTBLS3997 | MetaboLights
MetabolomicsIntegrated Multi-omics Analysis Identifies Diagnostic Biomarkers for Acute Coronary Syndrome in Type 2 Diabetes Mellitus Patients

Biomarkers for the early identification of acute coronary syndrome (ACS) risk remain inadequately investigated, particularly in patients with type 2 diabetes mellitus (T2DM), for whom timely clinical intervention may substantially enhance prognostic outcomes. The gut microbiota and serum metaboli...

2026-03-19 | MTBLS14087 | MetaboLights
TranscriptomicsElevated expression of AKR1C3 leads esophageal cancer resistant to ionizing radiation via modulation of oxidative stress (TE13)
With the aim to elucidate the etiology of radioresistance, we explored the genetic alterations in non-radioresistant vs. resistant esophageal cancer cells acquired by long-term fractionated radiation. We found AKR1C3, an aldo-keto reductase expressed seldom in most human tissues, expressed higher in...
ORGANISM(S): Homo sapiens 
2014-09-27 | E-GEOD-61816 | biostudies-arrayexpress
TranscriptomicsElevated expression of AKR1C3 leads esophageal cancer resistant to ionizing radiation via modulation of oxidative stress
With the aim to elucidate the etiology of radioresistance, we explored the genetic alterations in non-radioresistant vs. resistant esophageal cancer cells acquired by long-term fractionated radiation. We found AKR1C3, an aldo-keto reductase expressed seldom in most human tissues, expressed higher in...
ORGANISM(S): Homo sapiens 
2014-09-27 | E-GEOD-61620 | biostudies-arrayexpress
TranscriptomicsElevated expression of AKR1C3 leads esophageal cancer resistant to ionizing radiation via modulation of oxidative stress (KY170)
With the aim to elucidate the etiology of radioresistance, we explored the genetic alterations in non-radioresistant vs. resistant esophageal cancer cells acquired by long-term fractionated radiation. We found AKR1C3, an aldo-keto reductase expressed seldom in most human tissues, expressed higher in...
ORGANISM(S): Homo sapiens 
2014-09-27 | E-GEOD-61772 | biostudies-arrayexpress
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