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TranscriptomicsSmall RNA sequencing in normal and psoriatic skin
We report the application of Illumina small RNA sequencing to normal human skin, as well as uninvolved and involved psoriatic skin. By obtaining over 600 million qualified reads from 20 healthy controls and 47 psoriasis biopsies (uninvolved/involved), we have generated a complete small RNA profile i...
ORGANISM(S): Homo sapiens 
2011-08-19 | E-GEOD-31037 | biostudies-arrayexpress
UnknownDevelopment and validation of a bronchoalveolar lavage genomic classifier for acute cellular rejection.
Not available
S-EPMC12719680 | biostudies-literature
UnknownDeep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome.
Not available
S-EPMC3177648 | biostudies-literature
ProteomicsSILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.
Male sex predispose to many kidney diseases. Considering that androgens exert deleterious effects in a variety of cell types within kidney, we hypothesized that dihydrotestosterone (DHT) would impair the biology of the renal tubular cell by inducing changes in the proteome. We employed stable isotop...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080854 | MassIVE
UnknownSomatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Not available
S-EPMC5250619 | biostudies-literature
ProteomicsUrinary PRM analysis of early type 1 diabetes
Chronic hyperglycemia is known to disrupt the proteolytic milieu, initiating compensatory and maladaptive pathways in the diabetic kidney. Such changes in intrarenal proteolysis can be captured in the urinary peptidome. We thus examined the urinary peptidomes of otherwise healthy youths with type 1 ...
ORGANISM(S): Homo Sapiens 
2020-01-01 | PXD012389 | panorama
UnknownDiscovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer.
Not available
S-EPMC3013113 | biostudies-literature
GenomicsA Population Genomics Study Using a Disease-Targeted Cell model: Integration of cis-eQTLs Discovered in Human Primary Osteoblasts with GWAS of Bone Phenotypes

The common genetic variants associated with complex traits typically lie in non-coding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quanti...

phs000225.v1.p1 | EGA
UnknownOuter domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04.
Not available
S-EPMC3571475 | biostudies-literature
UnknownOncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.
Not available
S-EPMC6485942 | biostudies-literature
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