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MetabolomicsL-serine enables reducing the virulence of Acinetobacter baumannii and modulating the SIRT1 pathway to eliminate the pathogen

The emergence of high-virulent Acinetobacter baumannii strains increases the mortality of patients and seriously affects their prognosis, which motivates us to explore novel ways to control such infections. In this study, gas chromatography-mass spectrometry was adopted to explore the me...

2024-01-18 | MTBLS8966 | MetaboLights
TranscriptomicsMicroarray skeletal muscle miR-499 overexpressing mice
This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
2016-09-03 | E-GEOD-72581 | biostudies-arrayexpress
UnknownDetermination of Phenolic Acids Using Ultra-High-Performance Liquid Chromatography Coupled with Triple Quadrupole (UHPLC-QqQ) in Fruiting Bodies of Sanghuangporus baumii (Pilat) L.W. Zhou and Y.C. Dai.
Not available
S-EPMC10609702 | biostudies-literature
TranscriptomicsLymphocyte gene expression data from moderate stage HD patients and controls
Highly quantitative biomarkers of neurodegenerative disease remain an important need in the urgent quest for disease modifying therapies. For Huntington's disease (HD), a genetic test is available (trait marker), but necessary state markers are still in development. In this report, we describe a lar...
ORGANISM(S): Homo sapiens 
2007-08-15 | E-GEOD-8762 | biostudies-arrayexpress
TranscriptomicsDNA Methylation Mediated by a MicroRNA Pathway
In plants, the known microRNAs (miRNAs) are produced as ~21 nucleotide (nt) duplexes from their precursors by Dicer like 1 (DCL1). They are incorporated into Argonaute 1 (AGO1) protein to regulate target gene expression primarily through mRNA cleavage. We report here the discovery of a new class of ...
ORGANISM(S): Oryza sativa 
2010-03-12 | E-GEOD-20748 | biostudies-arrayexpress
UnknownLiang-Ge-San: a classic traditional Chinese medicine formula, attenuates acute inflammation via targeting GSK3β.
Not available
S-EPMC10338930 | biostudies-literature
Proteomicsto screen the Treg inhibitor and investigate its mechanism in tumor
No Treg-specific therapeutics has been approved for clinical use. Our project aim to screen the Treg inhibitor and investigate its mechanism in tumor.
ORGANISM(S): Homo sapiens (Human) 
2025-01-15 | PXD059236 | Pride
Human ip-ms runx1 
UnknownUtility of EST-derived SSR in cultivated peanut (Arachis hypogaea L.) and Arachis wild species.
Not available
S-EPMC2678122 | biostudies-literature
UnknownLiang-Ge-San, a Classic Traditional Chinese Medicine Formula, Attenuates Lipopolysaccharide-Induced Acute Lung Injury Through Up-Regulating miR-21.
Not available
S-EPMC6868520 | biostudies-literature
ProteomicsGlobal Proteomic Analysis of Lysine acetylation in Fusarium oxysporum
Lysine acetylation (Kac), a discovered post-translational modification, plays a key role in the regulation of diverse cellular processes. Fusarium oxysporumis a destructive necrotrophic fungal pathogen distributed worldwide with broad ranging hosts. However, the functions of Kac are unknown in Fus...
ORGANISM(S): Trypanosoma brucei 
2021-09-09 | PXD020479 | Pride
Lc-ms/ms Lysine acetylation Fusarium oxysporum 
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