PRMT1 is the predominant type I protein arginine methyltransferase responsible for generating monomethylarginine and asymmetric dimethylarginine (MMA and ADMA) in various protein substrates. It regulates numerous biological processes, including RNA metabolism, mRNA splicing, DNA damage repair, and c...
We performed stable isotope labeling of amino acids in cell culture (SILAC) and mass spectrometry (MS) analysis to identify potential acetylation sites on METTL3 in response to ectopic p300 expression.
