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MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
UnknownYuye Jinhua Qingre Tablets Attenuate Acute Pharyngitis by inhibiting the Complement Cascade and C5a/C5aR1 Axis
Not available
S-EPMC12376329 | biostudies-literature
UnknownChronic cough relief by allosteric modulation of P2X3 without taste disturbance.
Not available
S-EPMC10511716 | biostudies-literature
UnknownGSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6.
Not available
S-EPMC8458982 | biostudies-literature
UnknownUnderstanding interspecies drug response variations between human and rodent P2X7 receptors.
Not available
S-EPMC12673082 | biostudies-literature
ProteomicsORMDL3-mediated bronchial epithelial pyroptosis leads to lung inflammatory in obese asthmatic mice
Obese asthma is a chronic disease that poses a serious threat to children's health, resulting in more severe wheezing, earlier airway remodelling, and insensitivity to hormone therapy. Despite its clinical importance, knowledge on the underlying mechanisms of this disease remains limited. This study...
ORGANISM(S): Mus Musculus 
2023-07-07 | PXD043630 |
ProteomicsAD-MCI-CN proteomic data (LFQ, DDA)
This data included proteomic data of 57 Alzheimer's disease patients, 43 mild cognitive patients and 62 cognitively normal controls.
ORGANISM(S): Homo Sapiens 
2023-08-18 | PXD044672 |
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