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TranscriptomicsRAW264.7 cells were treated with KDO, IFN beta and 8Br
RAW 264.7 cells were stimulated with KDO (100 ng/ml), IFN-β (300 pM) and/or 8-Br 100 μM. These ligands were applied individually or in combination with KDO for 60 min and 120 min. Total RNA was extracted using TriPure (Roche) following its protocol. Keywords: designed RAW 264.7 cells were stimulat...
ORGANISM(S): Mus musculus 
2008-06-28 | E-GEOD-11449 | biostudies-arrayexpress
Genomicsena-DATASET-TAU-03-04-2017-19:28:40:078-460 - samples
Targeted resequencing of samples was done with TruSeq custom amplicon low input kit (TSCA-LI, Illumina). The oligo capture probes were designed to include a prefix of 8 random nucleotides at the 5 end of each probe. The assay is designed such that each targeted locus is annealed with two probes, res...
EGAD00001003275 | EGA
GenomicsSuppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down Syndrome
Children with Down Syndrome (DS) are prone to development of high risk B-cell precursor ALL (DS-ALL) that differs genetically from most sporadic pediatric ALLs. Increased expression of CRLF2, the receptor to thymic stromal lymphopoietin (TSLP) characterizes about half of DS-ALLs and also a subgroup ...
EGAS00001002410 | EGA
Genomicsena-DATASET-TAU-08-04-2017-14:02:11:924-149 - samples
Description not provided
EGAD00001003280 | EGA
GenomicsDAC for data acquired during the Down Syndrome acute lymphoblastic leukemia project. The project was performed with clinical samples of the AIEOP-BFM trial.
Data Access Committee EGAC00001000644
EGAC00001000644 | EGA
TranscriptomicsMajor Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), anti-CD40 (CD40L), LPS, and, to a l...
ORGANISM(S): Mus musculus 
2004-12-08 | E-GEOD-2050 | biostudies-arrayexpress
MetabolomicsRecombinant Production of Biliverdin IXβ and δ Isomers in the T7 Promoter Compatible Escherichia coli Nissle
The ability to obtain purified biliverdin IX (BVIX) isomers other than the commercially available BVIXα is limited due to the low yields obtained by the chemical coupled oxidation of heme. Chemical oxidation requires toxic chemicals, has very poor BVIX yields (<0.05%), and is not conducive to scalab...
2021-12-16 | MTBLS3555 | MetaboLights
ProteomicsThe Functions of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo
This dataset includes BioID for SEC23A and SEC23B. The paper describes the functional redundancy of these two gene paralogs in the context of human disease.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-09 | MSV000081703 | MassIVE
TranscriptomicsImpaired Natural Killer Cell Self-Education and 'Missing-Self' Responses in Ly49-Deficient Mice
Nimblegen arrays were used to perform aCGH analysis on 2 mice strains, one which lacks the Ly49 gene cluster and the parent strain which still has the cluster. A targeted knock-out of the cluster resulted in the rearrangment and deletion of the cluster. The aCGH experiment was performed to elucida...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-38372 | biostudies-arrayexpress
UnknownAspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8598213 | biostudies-literature
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