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TranscriptomicsPrognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non-Small Cell Lung Cancer
Background: The JBR.10 trial demonstrated significant survival benefit from adjuvant cisplatin/vinorelbine (ACT) in stage IB-II NSCLC (HR 0.69, p=0.04), but stage IB patients did not derive significant benefit (HR: 0.94, p= 0.79). We hypothesized that expression profiling could identify stage-indepe...
ORGANISM(S): Homo sapiens 
2010-09-09 | E-GEOD-14814 | biostudies-arrayexpress
TranscriptomicsValidation of a histology-independent prognostic gene signature for early stage, non-small cell lung cancer including stage IA patients
Background: Patients with early stage non-small cell lung carcinoma (NSCLC) may benefit from treatments based on more accurate prognosis. A 15-gene prognostic classifier for NSCLC was identified from mRNA expression profiling of tumor samples from the NCIC CTG JBR.10 trial. Here, we assessed its val...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-GEOD-50081 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of patient-derived xenografts identify high level “passenger” gene aberrations associated with better prognosis in non-small cell lung cancer
Patient-derived tumor xenografts (PDXs) increasingly are being used as preclinical models to study human cancers and to evaluate novel therapeutics, as they reflect clinical cancers more closely than established tumor cell lines. With >100 PDXs established from resected non-small cell lung carcinoma...
ORGANISM(S): Mus musculus 
2016-10-26 | E-GEOD-68929 | biostudies-arrayexpress
TranscriptomicsGenomic markers for malignant progression in pulmonary adenocarcinoma.
Bronchioloalveolar carcinoma (BAC), a subtype of lung adenocarcinoma (ADC) without stromal, vascular, or pleural invasion, is considered an in situ tumor with a 100% survival rate. However, the histological criteria for invasion remain controversial. BAC-like areas may accompany otherwise invasive a...
ORGANISM(S): Homo sapiens 
2008-07-01 | E-GEOD-11945 | biostudies-arrayexpress
UnknownProbing CP symmetry and weak phases with entangled double-strange baryons.
Not available
S-EPMC9159954 | biostudies-literature
UnknownExtracting the femtometer structure of strange baryons using the vacuum polarization effect.
Not available
S-EPMC11470094 | biostudies-literature
UnknownEmerging tobacco-related cancer risks in China: A nationwide, prospective study of 0.5 million adults.
Not available
S-EPMC4584499 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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