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TranscriptomicsEffect of BMP4 and noggin on gene expression in murine R1 ES cells
To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h. Undifferentiated R1 ES cells were trea...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-20527 | biostudies-arrayexpress
TranscriptomicsExpression profiling of aging liver in low-fat diet mice
Dietary interventions are effective ways to extend or shorten lifespan. By examining midlife hepatic gene expressions in mice under different dietary conditions, which resulted in different lifespans and aging-related phenotypes, we were able to identify genes and pathways that modulate the aging pr...
ORGANISM(S): Mus musculus 
2012-03-27 | E-GEOD-36836 | biostudies-arrayexpress
TranscriptomicsExpression profiling of the effect of high-fat diet, low-fat diet, CR and exercise on mice liver
Dietary interventions are effective ways to extend or shorten lifespan. By examining midlife hepatic gene expressions in mice under different dietary conditions, which resulted in different lifespans and aging-related phenotypes, we were able to identify genes and pathways that modulate the aging pr...
ORGANISM(S): Mus musculus 
2012-03-27 | E-GEOD-36838 | biostudies-arrayexpress
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