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UnknownTMT-based quantitative proteomics analysis of the effects of Jiawei Danshen decoction myocardial ischemia-reperfusion injury.

Background

Every year, approximately 17 million people worldwide die due to coronary heart disease, with China ranking second in terms of the death toll. Myocardial ischemia-reperfusion injury (MIRI) significantly influences cardiac function and prognosis in cardiac surgery patients. Jiawei ...
S-EPMC9749149 | biostudies-literature
UnknownEffectiveness and potential mechanism of Jiawei-Xiaoyao-San for hyperthyroidism: a systematic review.

Objectives

To evaluate the effectiveness and potential mechanism of traditional Chinese medicine Jiawei-Xiaoyao-San (JWXYS) as an adjunct or mono- therapy for antithyroid drugs (ATDs) in the treatment of hyperthyroidism.

Methods

Eight databases and three trial registries were searched...
S-EPMC10534980 | biostudies-literature
ProteomicsChronotoxici-plate Containing Rhythmic Liver Organoids for Drug Screening
The circadian clock coordinates the daily rhythmicity of biological processes, and its dysregulation is associated with various human diseases. Despite the direct targeting of rhythmic genes by many best-selling and WHO essential drugs, traditional approaches can’t satisfy the need of explore multi-...
ORGANISM(S): Mus Musculus 
PXD043268 |
ProteomicsMS assay of proteins after CO-IP with GPNMB antibody in hippocampus area
Three mice were excised at day 7 after pilocarpine treatment to induce abundant GPNMB expression (Figures 1 and 2). Hippocampal proteins were extracted and pulled down by anti-GPNMB immunoprecipitation for mass-spectrometer assay.
ORGANISM(S): Mus Musculus 
PXD066376 |
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