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ProteomicsMilk glycopeptide across lactation
Protein N-glycosylation is an essential post-translational modification (PTM) frequently occurring on human milk proteins. These PTMs assist in protecting the infant's health and function amongst others as competitive inhibitors of pathogen binding and immunomodulators. Due to the individual unique...
ORGANISM(S): Homo Sapiens 
2020-11-07 | PXD022415 | panorama
UnknownIdentification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation.
Not available
S-EPMC8629626 | biostudies-literature
UnknownFunctional analysis of a de novo mutation c.1692 del A of the PHEX gene in a Chinese family with X-linked hypophosphataemic rickets.
Not available
S-EPMC6719531 | biostudies-literature
UnknownMetabolomic analysis of anti-hypoxia and anti-anxiety effects of Fu Fang Jin Jing Oral Liquid.
Not available
S-EPMC3799728 | biostudies-literature
UnknownBu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway.
Not available
S-EPMC10478627 | biostudies-literature
TranscriptomicsMicroarray skeletal muscle miR-499 overexpressing mice
This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
2016-09-03 | E-GEOD-72581 | biostudies-arrayexpress
TranscriptomicsMediator Med23-deficiency Enhances Neural Differentiation of Embryonic Stem Cells through Modulating BMP Signaling
Unraveling the mechanisms underlying early neural differentiation of ESCs is crucial to the cell-based therapies of neurodegenerate diseases. Neural fate acquisition is proposed to be controlled by a “default” mechanism, for which the molecular regulation is not well understood. In this study, w...
ORGANISM(S): Mus musculus 
2015-03-05 | E-GEOD-64500 | biostudies-arrayexpress
UnknownHua-Tan-Sheng-Jing Decoction Treats Obesity With Oligoasthenozoospermia by Up-Regulating the PI3K-AKT and Down-Regulating the JNK MAPK Signaling Pathways: At the Crossroad of Obesity and Oligoasthenozoospermia.
Not available
S-EPMC9086321 | biostudies-literature
ProteomicsGlobal Lactylation Profiling Reveals Lactate-Driven Regulatory Mechanisms Promoting Tumor Progression in Oral Squamous Cell Carcinoma
Cancer cells often rely on aerobic glycolysis for metabolism, and lactylation, a newly discovered post-translational modification, significantly impacts molecular processes. This study comprehensively analyzes lactylation's role in oral squamous cell carcinoma (OSCC), providing initial insights into...
ORGANISM(S): Homo sapiens (Human) 
2024-08-23 | PXD047535 | Pride
Human Proteome Oral cancer 
ProteomicsGlobal Lactylation Profiling Reveals Lactate-Driven Regulatory Mechanisms Promoting Tumor Progression in Oral Carcinoma
Cancer cells often rely on aerobic glycolysis for metabolism, and lactylation, a newly discovered post-translational modification, significantly impacts molecular processes. This study comprehensively analyzes lactylation's role in oral squamous cell carcinoma (OSCC), providing initial insights into...
ORGANISM(S): Homo sapiens (Human) 
2024-08-23 | PXD047673 | Pride
Human Proteome Oral cancer 
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