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TranscriptomicsUndifferentiated pleomorphic sarcoma recapitulates the expressional profile of Subtype II Leiomyosarcoma
Background: Undifferentiated pleomorphic sarcoma (UPS), used to be called malignant fibrous histiocytoma (MFH), is a malignant soft tissue tumor of uncertain origin, and is characterized by morphology. UPS often share similar morphological characters with other sarcomas, especially Leiomyosarcoma. ...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-53844 | biostudies-arrayexpress
TranscriptomicsDifferent molecular pathways along with pathogenesis of three subtypes of Leiomyosarcoma
Leiomyosarcoma (LMS) is a malignant neoplasm of smooth muscle and is an aggressive soft tissue tumor, have complex genetic abnormalities and could be defined as three molecular subtypes. Since that the molecular heterogeneity of LMS, the pathogenesis analysis per subtype will be highly necessary and...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-54511 | biostudies-arrayexpress
TranscriptomicsStratification of Leiomyosarcoma molecular subtypes by 3' end RNA-sequencing: Toward precision medicine
Leiomyosarcoma (LMS) is a malignant neoplasm with smooth muscle differentiation. Little is known about its molecular heterogeneity and no targeted therapy currently exists for LMS. We demonstrate the existence of 3 molecular subtypes in a cohort of 99 cases and an independent cohort of 82 LMS. Tw...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-45510 | biostudies-arrayexpress
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