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TranscriptomicsPolyploidization of mesenchymal cells is associated with suppression of the non-coding RNA H19 and with reduced tumorigenicity
Mesenchymal stromal cells (MSCs) are used extensively in clinical trials; however, the potential for malignant transformation of MSCs has been raised. We examined the genomic stability versus the tumor forming capacity of multiple mouse MSCs. Murine MSCs have been shown to be less stable and more pr...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-39410 | biostudies-arrayexpress
TranscriptomicsExpression data from five independent murine BM MSC
Data collected in our laboratory show that independent murine MSC cultures react in a heterogeneous manner to Toll-like receptors (TLRs) activation. This array aims to investigate the molecular basis for the heterogeneity in the response of MSCs to TLR activation and its origin. For this array, 5 MS...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-50560 | biostudies-arrayexpress
TranscriptomicsFate changes leading to multipotency of isolated mesenchymal cells [Expression: Dense_vs_Sparse]
Mesenchymal populations include a fraction of cells exhibiting multipotency as well as others with limited differentiation range. It has been assumed that the mesenchymal cellular cascade is topped by a multipotent cell, which gives rise to progeny with diminishing differentiation potentials. Here ...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-48546 | biostudies-arrayexpress
GenomicsFate changes leading to multipotency of isolated mesenchymal cells [ChIP-Seq]
Mesenchymal populations include a fraction of cells exhibiting multipotency as well as others with limited differentiation range. It has been assumed that the mesenchymal cellular cascade is topped by a multipotent cell, which gives rise to progeny with diminishing differentiation potentials. Here ...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-48544 | biostudies-arrayexpress
TranscriptomicsFate changes leading to multipotency of isolated mesenchymal cells [Expression: Population_vs_Clone]
Mesenchymal populations include a fraction of cells exhibiting multipotency as well as others with limited differentiation range. It has been assumed that the mesenchymal cellular cascade is topped by a multipotent cell, which gives rise to progeny with diminishing differentiation potentials. Here ...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-48545 | biostudies-arrayexpress
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