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Protein-protein interaction within the MGM holocomplex has been investigated by chemical cross-linking mass spectrometry using EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide) cross-linker. Although this analysis was not exhaustive, we observed crosslinks between Alp4 and Alp6 along the length of...
ORGANISM(S): Schizosaccharomyces pombe 
2019-05-27 | PXD012624 | Pride
Increasing evidence suggests that age-related inflammation plays a pivotal role in osteoarthritis (OA) pathogenesis, but the mechanism is not fully understood. Here, we demonstrate that skin aging is an important driver of experimental OA progression in male mice via enhanced IL-36 receptor (IL-36R)...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD062165 | Pride
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