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CHEBI ID

CHEBI:15354 (3)
CHEBI:16566 (3)
CHEBI:138389 (2)
CHEBI:15698 (2)
CHEBI:15727 (2)
CHEBI:15728 (2)
CHEBI:15760 (2)
CHEBI:15940 (2)
CHEBI:1606 (2)
CHEBI:16390 (2)
CHEBI:16450 (2)
CHEBI:16827 (2)
CHEBI:17015 (2)
CHEBI:17154 (2)
CHEBI:17361 (2)
CHEBI:17620 (2)
CHEBI:17650 (2)
CHEBI:17715 (2)
CHEBI:18300 (2)
CHEBI:18344 (2)
CHEBI:1879 (2)
CHEBI:2274 (2)
CHEBI:24813 (2)
CHEBI:27468 (2)
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CHEBI:28635 (2)
CHEBI:28865 (2)
CHEBI:30865 (2)
CHEBI:31697 (2)

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Taurocholic acid (4)
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Valerylcarnitine (3)
(-)-Bilobalide (2)
(1-(2-hydroxypentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (2)
(22E,24R)-Stigmasta-4,22-diene-3,6-dione (2)
(2E,4E)-N-[2-(4-hydroxyphenyl)ethyl]dodeca-2,4-dienamide (2)
(2R)-6-amino-2-[[(2R)-2-amino-4-carboxybutanoyl]amino]hexanoic acid (2)

Study type

Transcription profiling by array (28)
RNA-seq of coding RNA (12)
ChIP-seq (4)
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Release Date

2021 (37)
2022 (29)
2024 (23)
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2020 (22)
2023 (21)
2015 (18)
2016 (17)
2017 (14)
2019 (13)
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2014 (12)
2011 (12)
2013 (10)
2008 (10)
2009 (8)
2010 (5)
2012 (3)
2007 (3)
2026 (3)
2006 (2)
2005 (1)
2004 (1)

Lab affiliation

Cell Signaling and Metabolism Group German Cancer Research Center (DKFZ) (2)
German Cancer Research Center (DKFZ) (2)
1)Program for Predictive and Personalized Medicine of Cancer, Germans Trias i Pujol Research Institute (PMPPC-IGTP), 08916 Badalona, Spain 2)Cancer and Leukemia Epigenetics and Biology Program, Josep Carreras Leukaemia Research Institute (IJC), Campus ICO-GTP-UAB, 08916 Badalona, Spain (1)
CeMM, Research Center for Molecular Medicine, Austrian Academy of Sciences, Austria (1)
Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Bellaterra, Barcelona 08193, Spain (1)
Department of Biology and Chemistry, Paul Scherrer Institute (PSI), Villigen, Switzerland (1)
Department of Microbiology, Immunobiology and Genetics, Max Perutz Labs, University of Vienna, Vienna BioCenter (VBC), Vienna, Austria (1)
Friedrich Miescher Institute for Biomedical Research, FMI, Switzerland (1)
Harvard Medical School (1)
Head of Proteomics and Metabolomics Facility (1)
Institut de Biologie Moléculaire des Plantes du CNRS Université de Strasbourg 12 rue du Général Zimmer 67084 Strasbourg Cedex France (1)
Institute of Ecology and Evolution, University of Bern, Baltzerstrasse 6, CH-3012 Bern, Switzerland (1)
Institute of Molecular Biology (IMB) Ackermannweg 4, 55128 Mainz (1)
Ludwig Boltzmann Institute Cancer Research, Vienna, Austria (1)
Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria (1)
Research Institute of Molecular Pathology (IMP), ViennaBioCenter (VBC), Campus-Vienna-Biocenter 1, 1030, Vienna, Austria (1)
The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA. Howard Hughes Medical Institute, New York, NY 10016, USA. (1)
Univ.-Prof. Dr., University of Vienna, Max Perutz Labs, Vienna Biocenter Campus (VBC) (1)
University of Bern, Department of Clinical Research, Proteomics and Mass Spectrometry Core Facility, 3010 Bern, Switzerland (1)

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Stage-specific control of early B cell development by the transcription factor Ikaros

Ikaros is an essential regulator of lymphopoiesis. Here, we studied the B-cell-specific function of Ikaros by conditional Ikzf1 inactivation in pro-B cells. B-cell development was arrested at an aberrant ‘pro-B’ cell stage characterized by increased cell adhesion and loss of pre-B cell receptor sign...

ORGANISM(S): Mus musculus

2014-02-09 | E-GEOD-53595 | biostudies-arrayexpress

Inducible PAX5 expression in a human B lymphoblastic leukemia cell line

Hypomorphic mutations of the transcription factor PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs). To identify PAX5-regulated genes in B-ALL, here we employ inducible expression of PAX5 in a human B-ALL cell line (REH) that harbors a loss-of-function mutation in PAX5. ...

ORGANISM(S): Homo sapiens

2014-06-18 | E-GEOD-57480 | biostudies-arrayexpress

Expression profiling of mouse bone marrow pre-B cells

Triplicate RNA-seq expression analysis of bone marrow pre-B cells isolated from mice, to demonstrate repertoire at the IgH locus Triplicate RNA-seq expression analysis of bone marrow pre-B cells

ORGANISM(S): Mus musculus

2014-06-18 | E-GEOD-52868 | biostudies-arrayexpress

Molecular role of the PAX5-ETV6 oncoprotein in promoting B cell acute lymphoblastic leukemia

PAX5 is a tumor suppressor in B-ALL, while the role of PAX5 fusion proteins in B-ALL development is largely unknown. Here we studied the function of PAX5-ETV6 and PAX5- FOXP1 in mice expressing these proteins from the Pax5 locus. Both proteins arrested Blymphopoiesis at the pro-B-to-pre-B cell trans...

ORGANISM(S): Mus musculus

2016-07-30 | E-GEOD-84987 | biostudies-arrayexpress

Pax5 restoration in a mouse model of B progenitor acute lymphoblastic leukemia

Hypomorphic mutations of PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs), however their functional consequences remain undefined. Here we employ advanced transgenic RNAi in mice to suppress endogenous Pax5 expression in the hematopoietic compartment in vivo, which co-o...

ORGANISM(S): Mus musculus

2014-06-18 | E-GEOD-52870 | biostudies-arrayexpress

Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia.

Not available

S-EPMC5350564 | biostudies-literature

Stage-specific control of early B cell development by the transcription factor Ikaros.

Not available

S-EPMC5790181 | biostudies-literature

HIV through the looking glass: insights derived from Hepatitis B.

Not available

S-EPMC4296901 | biostudies-literature

In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation.