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UnknownCD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia.
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S-EPMC4876311 | biostudies-literature
TranscriptomicsCPG stimulation for Gene Expression of unmutated B-CLL
The aim is to identify the differential gene expression profile of unmutated B-CLL stimulated with CPG. Two-condition experiment, CPG-stimulated B-CLL unmutated vs. Unstimulated B-CLL unmutated . Biological replicates: 9 unstimulated replicates, 9 CPG-stimulated replicates. Reference design;
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-30105 | biostudies-arrayexpress
TranscriptomicsCPG stimulation for Gene Expression of mutated B-CLL
The aim is to identify the differential gene expression profile of mutated B-CLL stimulated with CPG Two-condition experiment, CPG-stimulated B-CLL mutated vs. Unstimulated B-CLL mutated . Biological replicates: 8 unstimulated replicates, 8 CPG-stimulated replicates. Reference design;
ORGANISM(S): Homo sapiens 
2011-08-17 | E-GEOD-31360 | biostudies-arrayexpress
TranscriptomicsThe enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting
The ecto-enzyme CD38 is a marker of unfavorable prognosis for chronic lymphocytic leukemia (CLL) patients and an indicator of activation and proliferation of leukemic cells. Here we show that CD38 is enzymatically active in primary CLL cells and that its forced expression increases disease aggressiv...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-56369 | biostudies-arrayexpress
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