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MetabolomicsIntegrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play key roles in heart physiology, and this approach could pose a potential liability to cardiovascular health. Herein, using integr...
2022-09-20 | MTBLS795 | MetaboLights
TranscriptomicsMet synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (aCGH data).
Transcriptional profiling of normal and tumorigenic mouse mammary tissue. Mouse genotypes consist of wildtype, MMTV-Met, MMTV-Met;Trp53fl/+;Cre, and Trp53fl/+;Cre. Two-color common reference design. Samples consist of 4 normal tissues, 8 MMTV-Met tumors, 10 MMTV-Met;Trp53fl/+;Cre tumors, and 8 Trp53...
ORGANISM(S): Mus musculus 
2013-03-04 | E-GEOD-41632 | biostudies-arrayexpress
TranscriptomicsMet synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (miRNA expression data).
miRNA profiling of normal and tumorigenic mouse mammary tissue. Mouse genotypes consist of wildtype, MMTV-Met, MMTV-Met;Trp53fl/+;Cre, and Trp53fl/+;Cre. One-color design. Samples consist of 2 normal tissues, 7 MMTV-Met tumors, 8 MMTV-Met;Trp53fl/+;Cre tumors, and 8 Trp53;Cre tumors.
ORGANISM(S): Mus musculus 
2013-03-04 | E-GEOD-41723 | biostudies-arrayexpress
TranscriptomicsMet synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (mRNA expression data).
Transcriptional profiling of normal and tumorigenic mouse mammary tissue. Mouse genotypes consist of wildtype, MMTV-Met, MMTV-Met;Trp53fl/+;Cre, and Trp53fl/+;Cre. Two-color common reference design. Samples consist of 11 normal tissues, 8 MMTV-Met tumors, 14 MMTV-Met;Trp53fl/+;Cre tumors, and 8 Trp5...
ORGANISM(S): Mus musculus 
2013-03-04 | E-GEOD-41601 | biostudies-arrayexpress
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