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TranscriptomicsThe Human Airway Epithelial Basal Cell Transcriptome
Background. The human airway epithelium consists of 4 major cell types: ciliated, secretory, columnar and basal cells. During natural turnover and in response to injury, the airway basal cells function as stem / progenitor cells for the other airway cell types. The objective of this study is to bett...
ORGANISM(S): Homo sapiens 
2011-06-10 | E-GEOD-24337 | biostudies-arrayexpress
TranscriptomicsAirway Basal Cells of Healthy Smokers Express an Embryonic Stem Cell Signature Relevant to Lung Cancer
Activation of the human embryonic stem cell (hESC)-signature genes has been observed in various epithelial cancers. In this study, we found that the hESC signature is selectively induced in the airway basal stem/progenitor cell population of healthy smokers (BC-S), with a pat-tern similar to that ac...
ORGANISM(S): Homo sapiens 
2014-09-09 | E-GEOD-19722 | biostudies-arrayexpress
TranscriptomicsMultiomic (Joint snRNA/snATAC) sequencing data of intestinal crypts and epithelial only organoids derived from human fetal duodenum
Here, we used joint single-nuclei RNA-sequencing (snRNA-seq) and single-nuclei ATAC sequencing (scATAC) to profile freshly isolated crypts from the human fetal intestine and matched intestinal epithelial only organoids (also known as enteroids) derived from these crypts after one passage of in vitro...
ORGANISM(S): Homo sapiens 
2022-07-16 | E-MTAB-11908 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of intestinal epithelial organoids derived from human fetal duodenum
Here, we used single-cell RNA-sequencing (scRNA-seq) to profile intestinal epithelial only organoids (also known as enteroids) from human fetal duodenum after one passage of in vitro growth. Organoids were grown in the standard 25% LWRN media with either 100 ng/ml of EGF or 1 ng/ml of EREG added.
ORGANISM(S): Homo sapiens 
2022-07-17 | E-MTAB-11912 | biostudies-arrayexpress
TranscriptomicsscRNAseq of human fetal duodenum, 70 DPC
We performed single cell RNA sequencing (scRNA-seq) of human fetal duodenal tissue samples from a single individual biological specimen at 70 days post-conception (DPC). The data set is composed of cells from diverse intestinal lineages. Lineages captured include epithelium, mesenchyme, immune, neur...
ORGANISM(S): Homo sapiens 
2025-07-30 | E-MTAB-15358 | biostudies-arrayexpress
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