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Marine cyanobacteria are thought to be the most sensitive of the phytoplankton groups to copper toxicity, yet little is known of the transcriptional response of marine Synechococcus to copper shock. Global transcriptional response to two levels of copper shock was assayed in both a coastal and an o...
ORGANISM(S): Synechococcus sp. CC9311 
Copper toxicity response influences mesotrophic Synechococcus community structure
Cryptococcus neoformans is an invasive human fungal pathogen, which causes pneumonia and meningoencephalitis in both healthy and immunodeficient individuals, resulting 181,100 deaths each year. Studies have demonstrated that copper detoxification machineries play critical functions in modulating C. ...
ORGANISM(S): Cryptococcus Neoformans Var. Grubii H99 
2021-02-09 | PXD024098 |
Picocyanobacteria from the genus Synechococcus are ubiquitous in ocean waters. Their phylogenetic and genomic diversity suggests ecological niche differentiation, but the selective forces influencing this are not well defined. Marine picocyanobacteria are sensitive to Cu toxicity, so adaptations to ...
ORGANISM(S): Bacteria Synechococcus sp. CC9311 Synechococcus sp. CC9902 
2016-10-28 | GSE89262 | GEO
Gene expression response to copper toxicity between coastal and open ocean strains of marine Synechococcus
Screening for genes that promote copper toxicity in a cell model of Wilson disease
Impact of copper oxide particle dissolution on lung epithelial cell toxicity: response characterization using global transcriptional analysis
RNA-seq was used to assess mRNA transcript abundance in wild type and fra2Δ S. cerevisiae (BY4741) cells treated with 2-(6-benzyl-2-pyridyl)quinazoline (BPQ) and CuSO4. BPQ potentiates copper toxicity and in yeast, in common with other organisms, a major cause of copper toxicity is damage of iron-su...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-04 | GSE54045 | GEO
RNA-seq was used to assess mRNA transcript abundance in wild type and fra2M-NM-^T S. cerevisiae (BY4741) cells treated with 2-(6-benzyl-2-pyridyl)quinazoline (BPQ) and CuSO4. BPQ potentiates copper toxicity and in yeast, in common with other organisms, a major cause of copper toxicity is damage of i...
ORGANISM(S): Saccharomyces cerevisiae 
Marine cyanobacteria are thought to be the most sensitive of the phytoplankton groups to copper toxicity, yet little is known of the transcriptional response of marine Synechococcus to copper shock. Global transcriptional response to two levels of copper shock was assayed in both a coastal and an op...
ORGANISM(S): Parasynechococcus marenigrum WH 8102 Synechococcus sp. CC9311 
2009-07-01 | GSE13910 | GEO
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