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GenomicsE2F7 represses a transcriptional network of oscillating cell cycle genes to control S-phase progression.
E2F transcription factors are known to be important for timely activation of G1/S and G2/M genes required for cell cycle progression, but transcriptional mechanisms for deactivation of cell cycle regulated genes are unknown. Here, we show that E2F7 is highly expressed during mid to late S-phase, occ...
ORGANISM(S): Homo sapiens 
2012-01-04 | E-GEOD-32673 | biostudies-arrayexpress
UnknownCyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression
Not available
S-SCDT-EMBOJ-2018-101430 | biostudies-other
TranscriptomicsMicroarray gene expression profiling in E2f7 and E2f8 deleted liver compared to control in mice
Two condition experiment were compared: Wild type vs. E2f7/8 dko mouse liver. Biological replicates: two wild type replicates and two E2f7/8 dko replicates for each of 3-wk, 4-wk and 16-wk age groups.
ORGANISM(S): Mus musculus 
2012-11-05 | E-MEXP-3384 | biostudies-arrayexpress
TranscriptomicsBW001
E2F transcription factors are known to be important for timely activation of G1/S and G2/M genes required for cell cycle progression, but transcriptional mechanisms for deactivation of cell cycle-regulated genes are unknown. Here, we show that E2F7 is highly expressed during mid to late S-phase, occ...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-33448 | biostudies-arrayexpress
TranscriptomicsWB001A: Genome-wide analysis reveals NRP1 as a critical HIF1-E2F7 target gene in the regulation of motor neuron guidance in vivo
In this study, we explored the existence of a transcriptional network co-regulated by E2F7 and HIF1α, as we show that expression of E2F7, like HIF1α, is induced in hypoxia, and because of the previously reported ability of E2F7 to interact with HIF1α. Our genome-wide analysis uncovers a transcrip...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-66750 | biostudies-arrayexpress
UnknownPIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis
Not available
S-SCDT-EMBOR-2020-50893-T | biostudies-other
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