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We used Nimblegen HD aCGH to detect copy-number variants between tumor and ear control-DNA samples from heterozygous and homozygous Tp53C273X knockout rats Comparison of tumor DNA with ear control-DNA from the same animal
ORGANISM(S): Rattus norvegicus 
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
BfHL's, spor zonder BfNHL's en BfHL4
ORGANISM(S): Homo sapiens 
CRISPR-Cas9 was used to generate HNF1a mutants (+/- and -/-) in human embryonic stem cell lines and used an in vitro differentiation system to study pancreatic beta cell differentiation and subsequent function of the derivative beta cells.
ORGANISM(S): Homo sapiens 
We investigated the kinetics, breadth, magnitude, and level of cross-reactivity of IgG antibodies against SARS-CoV-2 and heterologous seasonal (HCoV-NL63, -229E, -OC43 and -HKU1) and epidemic coronaviruses (SARS-CoV, hCoV-MERS) at the clonal level in patients with mild or severe COVID-19 as well as ...
ORGANISM(S): Homo sapiens 
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