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Abstract: In dietary polyphenol exposure studies, annotation and identification of urinary metabolites present at low (micromolar) concentrations are major obstacles. To determine the biological activity of specific components, it is necessary to have the correct structures and the quantification of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-03 | MSV000081878 | GNPS
Abstract: High-mass resolution multi-stage mass spectrometry (MS(n)) fragmentation was tested for differentiation and identification of metabolites, using a series of 121 polyphenolic molecules. The MS(n) fragmentation approach is based on the systematic breakdown of compounds, forming a so-called s...
ORGANISM(S): Polyphenol Standard Compounds (reference Compounds) 
2018-01-03 | MSV000081880 | GNPS
Rat small intestine precision cut slices were exposed for 6 hours to in vitro digested yellow (YOd) or white onion extracts (WOd) that was followed by transcriptomics analysis. The digestion was performed to mimic the digestion that in vivo takes place in the saliva, stomach and small intestine. A m...
ORGANISM(S): Rattus norvegicus 
Abstract of the study: Advanced analytical approaches consisting of both LC-LTQ-Orbitrap Fourier transformed (FT)-MS and LC-time-of-flight-(TOF)-MS coupled to solid-phase extraction (SPE) NMR were used to obtain more insight into the complex phenolic composition of tea. On the basis of the combined...
ORGANISM(S): Camellia Sinensis (ncbitaxon:4442) 
2018-01-03 | MSV000081877 | GNPS
Transcriptional analysis upon the overexpression of the folate gene cluster on a high copy plasmid when compared to an empty vector in the lactic acid bacterium L. plantarum. The transcriptional response was determined for both strains in the presence and absence of pABA thereby using the hybridisat...
ORGANISM(S): Lactobacillus plantarum 
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