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TranscriptomicsIncreased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA
Transcriptome analysis is of great interest in clinical research, where significant differences between individuals can be translated into biomarkers of disease. Although next generation sequencing provides robust, comparable and highly informative expression profiling data, with several million of ...
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-33701 | biostudies-arrayexpress
TranscriptomicsBaker_Stem_Cells
Gene expression studies of human embryonic stem cells undergoing directed differentiation to endothelial cells to identify key transcriptional changes during differentiation
ORGANISM(S): Homo sapiens 
2013-03-19 | E-MTAB-1510 | biostudies-arrayexpress
TranscriptomicsPhenotypically concordant and discordant monozygotic twins display different DNA copy number variation profiles (SNP)
The exploration of copy number variation (CNV), notably of somatic cells, is an understudied aspect of genome biology. Any differences in the genetic make-up between twins derived from the same zygote represent an extreme example of somatic variation. We studied 19 pairs of monozygotic twins with ei...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9608 | biostudies-arrayexpress
UnknownDecay of Sexual Trait Genes in an Asexual Parasitoid Wasp.
Not available
S-EPMC5381511 | biostudies-literature
UnknownRecommendations for a nomenclature system for reporting methylation aberrations in imprinted domains.
Not available
S-EPMC5873357 | biostudies-literature
UnknownMutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2.
Not available
S-EPMC3113345 | biostudies-literature
TranscriptomicsIntrinsic glioma subtypes in EORTC 26951 (part 1)
Background: Intrinsic glioma subtypes (IGS) are molecularly similar tumors that can be identified based on unsupervised gene-expression analysis. Here, we have evaluated the clinical relevance of these subtypes within EORTC26951, a randomized phase III clinical trial investigating adjuvant procarbaz...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43107 | biostudies-arrayexpress
TranscriptomicsIntrinsic glioma subtypes in EORTC 26951 (part 6)
Background: Intrinsic glioma subtypes (IGS) are molecularly similar tumors that can be identified based on unsupervised gene-expression analysis. Here, we have evaluated the clinical relevance of these subtypes within EORTC26951, a randomized phase III clinical trial investigating adjuvant procarbaz...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43353 | biostudies-arrayexpress
TranscriptomicsIntrinsic glioma subtypes in EORTC 26951 (part 4)
Background: Intrinsic glioma subtypes (IGS) are molecularly similar tumors that can be identified based on unsupervised gene-expression analysis. Here, we have evaluated the clinical relevance of these subtypes within EORTC26951, a randomized phase III clinical trial investigating adjuvant procarbaz...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43115 | biostudies-arrayexpress
TranscriptomicsIntrinsic glioma subtypes in EORTC 26951 (part 2)
Background: Intrinsic glioma subtypes (IGS) are molecularly similar tumors that can be identified based on unsupervised gene-expression analysis. Here, we have evaluated the clinical relevance of these subtypes within EORTC26951, a randomized phase III clinical trial investigating adjuvant procarbaz...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43113 | biostudies-arrayexpress
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