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UnknownMonodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications.
Complexes are emerging as promising alternatives for the treatment of neglected parasitic and viral infections, which urgently require new therapeutic strategies due to limited effective drugs. In this study, a series of [Pt(II)(phpy)(PR3)Cl] complexes, where phpy is 2-phenylpyridine, and...
S-EPMC12913238 | biostudies-literature
UnknownASSOBRAFIR clinical practice guidelines in respiratory physical therapy: Exercise-based interventions in people with chronic obstructive pulmonary disease (COPD).

Background

Exercise training is essential in pulmonary rehabilitation (PR) for individuals with chronic obstructive pulmonary disease (COPD). In Brazil, physical therapists typically deliver exercise in PR. This document presents ASSOBRAFIR recommendations for prescribing exercise training f...
S-EPMC12552906 | biostudies-literature
UnknownA novel nonsense mutation in the tyrosinase gene is related to the albinism in a capuchin monkey (Sapajus apella).

Background

Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. The OCA phenotype may be caused by mutations in the tyrosinase gene (TYR), which expresses the tyrosinase enzyme and has an important role in the synth...
S-EPMC5420114 | biostudies-literature
Unknown<i>In Situ</i> Luminescence of Self-Assembled Eu(III)-Naphthoic Acid Complex in Langmuir and LB Films.
Highly luminescent nanostructured films with controlled molecular organization may find applications in various areas, ranging from new drug delivery systems to solid-state lighting. In this work, we synthesized and characterized amphiphilic complexes [Ln(dion)3(H2O)(DMSO)] whe...
S-EPMC12548350 | biostudies-literature
UnknownVertical stratification of insect abundance and species richness in an Amazonian tropical forest.
Tropical forests are among the most biodiverse biomes on the planet. Nevertheless, quantifying the abundance and species richness within megadiverse groups is a significant challenge. We designed a study to address this challenge by documenting the variability of the insect fauna across a vertical c...
S-EPMC8810858 | biostudies-literature
UnknownEpidemiological characterization of rare diseases in Brazil: A retrospective study of the Brazilian Rare Diseases Network.

Background

The Brazilian Policy for Comprehensive Care for People with Rare Diseases was implemented in 2014; however, national epidemiological data on rare diseases (RDs) are scarce and mainly focused on specific disorders. To address this gap, University Hospitals, Reference Services for N...
S-EPMC11523578 | biostudies-literature
UnknownThe Toxicity of Poly(acrylonitrile-styrene-butadiene) Microplastics toward Hyalella azteca Is Associated with Biofragmentation and Oxidative Stress.
Acrylonitrile-butadiene-styrene (ABS) is a thermoplastic copolymer commonly used in the electronics, automotive, and construction industries. In the aquatic environment, the formation of microplastics from larger-sized plastic waste occurs naturally, induced by physical, chemical, and biological pro...
S-EPMC11752492 | biostudies-literature
UnknownPolyphenol-Rich Diets Exacerbate AMPK-Mediated Autophagy, Decreasing Proliferation of Mosquito Midgut Microbiota, and Extending Vector Lifespan.

Background

Mosquitoes feed on plant-derived fluids such as nectar and sap and are exposed to bioactive molecules found in this dietary source. However, the role of such molecules on mosquito vectorial capacity is unknown. Weather has been recognized as a major determinant of the spread of de...
S-EPMC5061323 | biostudies-literature
UnknownOrganizational factors associated with adherence to low tidal volume ventilation: a secondary analysis of the CHECKLIST-ICU database.

Background

Survival benefit from low tidal volume (VT) ventilation (LTVV) has been demonstrated for patients with acute respiratory distress syndrome (ARDS), and patients not having ARDS could also benefit from this strategy. Organizational factors may play a role on adherence to ...
S-EPMC7266115 | biostudies-literature
UnknownGenomic epidemiology reveals the impact of national and international restrictions measures on the SARS-CoV-2 epidemic in Brazil.
Brazil has experienced some of the highest numbers of COVID-19 cases and deaths globally and from May 2021 made Latin America a pandemic epicenter. Although SARS-CoV-2 established sustained transmission in Brazil early in the pandemic, important gaps remain in our understanding of virus transmission...
S-EPMC8978948 | biostudies-literature
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