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ProteomicsTrypanosoma brucei Trypanothione synthetase modification by Ebselen
Identification of Ebselen modification sites on T. brucei Trypanothione synthetase
ORGANISM(S): Trypanosoma brucei Escherichia coli 
2022-04-04 | PXD027729 | Pride
Ebselen Trypanothione synthetase 
TranscriptomicsGene expression profile during Ebselen treatment in budding yeast
Ebselen is synthetic selenium containing organic compound. It exhibits glutathione peroxidase (GSH-Px) like activity hence acts as a potent antioxidant therefore has been widely used in the treatment of various diseases. In contrast, certain studies also demonstrate its toxic nature; however its mec...
ORGANISM(S): Schizosaccharomyces pombe Saccharomyces cerevisiae 
2023-01-28 | GSE41711 | GEO
TranscriptomicsEbselen as a promising treatment in mitochondrial diseases: focus on Barth syndrome and complex I deficiencies
Over the past decade, significant progress improved mitochondrial disorders diagnosis, but effective therapies remain lacking. A drug screening identified Ebselen (EBS) as enhancing oxidative phosphorylation-dependent growth in a yeast model of Barth syndrome, a cardiomyopathy caused by defective ca...
ORGANISM(S): Saccharomyces cerevisiae 
2026-09-03 | E-MTAB-16519 | biostudies-arrayexpress
Genomics
Ebselen inhibits PRRSV replication
PRJNA1304470 | ENA
GenomicsEbselen as a promising treatment in mitochondrial diseases: focus on Barth syndrome and complex I deficiencies
Ebselen as a promising treatment in mitochondrial diseases: focus on Barth syndrome and complex I deficiencies
PRJEB106496 | ENA
UnknownAntibacterial Activity of Ebselen.
Not available
S-EPMC9864093 | biostudies-literature
UnknownThe Potential Use of Ebselen in Treatment-Resistant Depression.
Not available
S-EPMC9030939 | biostudies-literature
Genomics
Ebselen Exhibits Antimicrobial Activity Against Clostridioides difficile By Disrupting Cysteine Metabolism
PRJNA647225 | ENA
UnknownEfficacy of Ebselen Against Invasive Aspergillosis in a Murine Model.
Not available
S-EPMC8260993 | biostudies-literature
UnknownEbselen Interferes with Alzheimer's Disease by Regulating Mitochondrial Function.
Not available
S-EPMC9312019 | biostudies-literature
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