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TranscriptomicsCRISPR RNA-seq from K562 (ENCSR039SOI)
RNA-seq on K562 cells treated with a CRISPR gRNA against GEMIN2. (GEMIN2-BGKcLV17) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2021-06-15 | GSE176730 | GEO
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Transcriptomicstotal RNA-seq from astrocyte (ENCSR129VBC)
PGP1 derived astrocytes For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2021-06-15 | GSE176716 | GEO
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TranscriptomicsThe molecular landscape of neural differentiation inthe developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis
In this work, Michki et. al. isolate neurons and neural progenitors from the developing Drosophila brain. Through a combination of in silico and in situ techniques, they map out the expression dynamics of a variety of molecular factors that may play a role in specifying terminal neural fates at the ...
ORGANISM(S): Drosophila melanogaster 
2021-05-05 | GSE153723 | GEO
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GenomicsAffymetrix SNP array data for a Diffuse Large B-cell Lymphoma case with a TERT promoter variant who later developed Chronic Myelomonocytic Leukemia
TERT promoter variants are well known in solid tumors. However, less is known in hematological malignancies, thus we screened a large series of MDS and MDS/MPN.
ORGANISM(S): Homo sapiens 
2021-06-20 | GSE133150 | GEO
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TranscriptomicsBromodomain containing 9 (BRD9) regulates macrophage inflammatory responses and modulates glucocorticoids receptor activity [RNA-seq]
In macrophages, homeostatic and immune signals induce distinct sets of transcriptional responses, defining the cellular identity and function. The activity of lineage specific and signal induced transcription factors are regulated by chromatin accessibility and other epigenetic modulators. Glucocort...
ORGANISM(S): Mus musculus 
2021-08-23 | GSE175584 | GEO
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GenomicslncRNA-seq profiling for primary mouse cortical neurons
To understand the factors influencing gRNA performance for CRISPR-TO system, we performed lncRNA-seq profiling through Novogene Corporation Inc for total RNA extracted from 6 DIV primary mouse cortical neurons dissected from 3 litters of P0 pups of C57BL/6J mice.
ORGANISM(S): Mus musculus 
2025-03-31 | GSE278329 | GEO
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GenomicsSet1 targets gene with essential identity and tumor suppressing functions in planarian stem cells. Mnase-ChIP was used to validate a wide histone H3K4me3 peak width signature.
Previous publications have reported the significance of a wide histone H3K4me3 signature at essential genes in many organisms and cell types. Most of these published datasets were produced using cross-linking ChIP-seq, in which the chromatin was chemically cross-linked using formadehyde and then mec...
ORGANISM(S): Drosophila melanogaster Schmidtea mediterranea 
2021-07-26 | GSE180591 | GEO
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TranscriptomicsSingle-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features
This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Homo sapiens 
2025-08-11 | GSE303592 | GEO
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TranscriptomicsSingle-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features [bulk-RNAseq]
In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true for keloids, the example of pathological scarring exploited in this study, as there is no animal mo...
ORGANISM(S): Homo sapiens 
2025-08-11 | GSE303591 | GEO
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TranscriptomicsCRISPR RNA-seq from HepG2 (ENCSR444IOJ)
RNA-seq on HepG2 cells treated with a CRISPR gRNA against MORC2. (MORC2-BGHcLV20) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2021-06-15 | GSE177254 | GEO
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