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siRNAs with dN are a promising and easy approach to characterize essential genes by minimizing the off-target effect in cancer cells. mRNA profiles of HCT 116 cells after the transfection of siRNAs or blank control by deep sequencing, using HiSeq 2000
ORGANISM(S): Homo sapiens 
Plants engineered for abiotic stress tolerance may soon be commercialized. The engineering of these plants typically involves the manipulation of complex multigene networks and may therefore have a greater potential to introduce pleiotropic effects than the simple monogenic traits that currently dom...
ORGANISM(S): Arabidopsis thaliana 
CH891(1C), CH891(2A),CH891(1C+2A) and CH891 were sampled in leaf tissue at heading stage. The differentially expressed proteins in the proteome between transgenic restorer lines and recurrent parents were compared, and their functional annotation and enrichment analysis were performed
ORGANISM(S): Oryza sativa (Rice) 
2023-03-11 | PXD033443 | Pride
DNA microarray analysis has been proved to be an effective method in investigating unintended effects in genetically modified (GM) crops. But the distribution of differentially expressed genes in GM crops remains unclear. So the results of microarray analysis might be invalid for assessment of unint...
ORGANISM(S): Oryza sativa Indica Group 
The role of Pantonâ??Valentine leukocidin (PVL) in Staphylococcus aureus pathogenesis is controversial. Here, we show that an unintended point mutation in the agr P2 promoter of S.aureus caused the phenotypes in gene regulation and murine pneumonia attributed to PVL by Labandeiraâ??Rey et al. (Scien...
ORGANISM(S): Staphylococcus aureus 
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