van Engelen B G M BG

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Transcription profiling of ovarium cancer samples from patients with tumors of different stages, sensitivity to platinum chemotherapy and with no disease recurrence, recurrence or progression to evaluate models of clinical behaviour

Ovarian cancer is the leading cause of death in gynaecological malignancies in women. However, currently there are no clinical or pathologic parameters available that can reliably predict clinical outcome. In a previously published pilot study we explored the performance of microarrays in predicting...

ORGANISM(S): Homo sapiens

2007-12-31 | E-MEXP-995 | biostudies-arrayexpress

Transcription profiling of ovarium cancer samples from patients with tumors of different stages and sensitivity to platinum chemotherapy treatment

We investigated whether prognostic information is reflected in the expression patterns of ovarian carcinoma samples. RNA obtained from seven FIGO stage I without recurrence, seven platin-sensitive advanced-stage (III or IV), and six platin-resistant advanced-stage ovarian tumors was hybridized on a ...

ORGANISM(S): Homo sapiens

2007-02-10 | E-MEXP-979 | biostudies-arrayexpress

Transcription profiling of testis from Sertoli cell-selective androgen receptor knockout mice and wild type mice to unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis

To unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis, testicular gene expression was compared in mice with a Sertoli cell-selective androgen receptor knockout (SCARKO) and littermate controls on postnatal d 10. At this age testicular cell composition is still com...

ORGANISM(S): Mus musculus

2007-09-25 | E-GEOD-2259 | biostudies-arrayexpress

Large-scale Proteomics Profiling of Peripheral Blood of DM1 patients identifies biomarkers for disease severity and physical activity - Validation cohort

Myotonic Dystrophy type 1 (DM1) is a progressive multisystem disease with large heterogeneity in disease onset, symptom development, progression rates and severity. This poses significant challenges to the design of clinical trials. To overcome some of these challenges, this study aims to identify p...

ORGANISM(S): Homo sapiens (Human)

2026-01-19 | PXD060035 | Pride

Scapular dyskinesis in myotonic dystrophy type 1: clinical characteristics and genetic investigations.

Not available

S-EPMC6851043 | biostudies-literature

Dominant mutations in KBTBD13, a member of the BTB/Kelch family, cause nemaline myopathy with cores.

Not available

S-EPMC2997379 | biostudies-literature

KBTBD13 is an actin-binding protein that modulates muscle kinetics.

Not available

S-EPMC6994151 | biostudies-literature

Cut from the same cloth? investigating the personality of interventional and surgical cardiovascular specialists.