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TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepatocellular carninoma HepG2 cell lines exposed to single dose of Benzo[a]pyrene (BaP) in a time-course over 60 hours and 11 time points
Not available
ORGANISM(S): ATCC 
2010-07-01 | E-TOXM-23 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepatocellular carninoma HepG2 cell lines exposed to single dose of Benzo[a]pyrene (BaP) in a time-course over 60 hours and 11 time points
Not available
ORGANISM(S): Homo sapiens 
2010-07-01 | E-TOXM-22 | biostudies-arrayexpress
TranscriptomicsDietary titanium dioxide (E171) increases systemic ROS levels and alters the colon transcriptome – Evidence from a human dietary intervention study
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
2025-09-30 | E-MTAB-15089 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP, and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h
Direct comparison of the hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h.
ORGANISM(S): Homo sapiens 
2010-04-15 | E-MEXP-2458 | biostudies-arrayexpress
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