Sort   by:  
 Page size 
ProteomicsProteolytic activity of surface exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile
To survive in the host, pathogenic bacteria need to be able to react to the unfavourable conditions that they encounter, like low pH, elevated temperatures, antimicrobial peptides and many more. These conditions may lead to unfolding of envelope proteins and this may be lethal. One of the mechanisms...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2025-11-11 | PXD050242 | Pride
Acid stress Clostridioides difficile Pdz domain Surface proteins Dimethyl labeling Htra Gene regulation Protease Lc-ms/ms 
ProteomicsBiochemical and structural characterization of PPEP-3 from Geobacillus thermodenitrificans
The members of the group of Pro-Pro endopeptidases (PPEPs) are secreted bacterial endoproteases that display a unique preference for hydrolyzing their substrates between two proline residues. The active site cleft of PPEPs accommodates the six substrate residues P3 to P3’, and the interactions betwe...
ORGANISM(S): Geobacillus thermodenitrificans 
2025-11-11 | PXD061585 | Pride
Geobacillus thermodenitrificans Macromolecular x-ray crystallography Zinc metallopeptidase Mass spectrometry Substrate specificity Pro-pro endopeptidase-3 
UnknownOriginal COVID-19 priming regimen impacts the immunogenicity of bivalent BA.1 and BA.5 boosters.
Not available
S-EPMC11102539 | biostudies-literature
Sort   by:  
 Page size