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UnknownEvaluating the Application of the Mental Model Mapping Tool (M-Tool).
Not available
S-EPMC8712333 | biostudies-literature
MetabolomicsLimited survival and impaired hepatic fasting metabolism of glucose, amino acids and lipids in mice with constitutive Rag GTPase signaling
The mechanistic target of rapamycin complex 1 (mTORC1) integrates cellular nutrient signaling and hormonal cues to control metabolism. We have previously shown that constitutive nutrient signaling to mTORC1 by means of genetic activation of RagA (RagAGTP) in mice resulted in a fatal energetic crisis...
2021-05-11 | MTBLS2397 | MetaboLights
MetabolomicsLipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy
As a consequence of impaired glucose or fatty acid metabolism, bioenergetic stress in skeletal muscles may trigger myopathy and rhabdomyolysis. Genetic mutations causing loss of function of the LPIN1 gene frequently lead to severe rhabdomyolysis bouts in children, though the metabolic alterations an...
2019-01-07 | MTBLS750 | MetaboLights
ProteomicsDesign and experimental evaluation of a minimal, innocuous watermarking strategy to distinguish near-identical DNA and RNA sequences
F. Boonekamp et al., (2019) describe an innocuous watermarking strategy for coding regions that enables the discrimination of DNA and mRNA by sequencing through a k-mer approach and facilitates selective editing of watermarked and non-watermarked sequences. Shot-gun proteomics (LFQ) was performed on...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-09-21 | PXD016914 | Pride
Yeast Lfq Proteomics 
TranscriptomicsAn alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme
Most available knowledge on fungal arginine metabolism is derived from studies on Saccharomyces cerevisiae, in which arginine catabolism is initiated by releasing urea via the arginase reaction. Orthologs of the S. cerevisiae genes encoding the first three enzymes in the arginase pathway were cloned...
ORGANISM(S): Kluyveromyces lactis 
2014-07-16 | E-GEOD-56060 | biostudies-arrayexpress
UnknownDiscovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase from Rhodococcus erythropolis.
Not available
S-EPMC11705230 | biostudies-literature
TranscriptomicsA Saccharomyces cerevisiae strain with a minimal complement of glycolytic genes reveals strong redundancies in central metabolism
As a result of ancestral whole genome and small-scale duplication events, the genome of Saccharomyces cerevisiaeM-bM-^@M-^Ys, and of many eukaryotes, still contain a substantial fraction of duplicated genes. In all investigated organisms, metabolic pathways, and more particularly glycolysis, are spe...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-06 | E-GEOD-63884 | biostudies-arrayexpress
UnknownA mandatory indication-registration tool in hospital electronic medical records enabling systematic evaluation and benchmarking of the quality of antimicrobial use: a feasibility study.
Not available
S-EPMC8254448 | biostudies-literature
UnknownDo malpractice claim clinical case vignettes enhance diagnostic accuracy and acceptance in clinical reasoning education during GP training?
Not available
S-EPMC10294315 | biostudies-literature
UnknownCRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus.
Not available
S-EPMC5718131 | biostudies-literature
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