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TranscriptomicsMicroarray analysis of striatal tissue of wild type and Ezh1/Ezh2 dKO mice at 6 weeks, 3 months, and 6 months
Normal brain function critically depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions. The fidelity of neuronal specification is contingent upon the robustness of the transcriptional program that supports the neuron ty...
ORGANISM(S): Mus musculus 
2016-07-29 | E-GEOD-84243 | biostudies-arrayexpress
GenomicsAUTS2 confers transcriptional activation to PRC1 in the CNS (ChIP-Seq)
Naturally occurring variations of Polycomb Repressive Complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that include, surprisingly, Autism Susceptibility Candidate 2 (AUTS2). While AUTS2 is often disrupted in patients with neuronal disorders, the underlying ...
ORGANISM(S): Mus musculus 
2014-12-18 | E-GEOD-60409 | biostudies-arrayexpress
TranscriptomicsAUTS2 confers transcriptional activation to PRC1 in the CNS (RNA-Seq)
Naturally occurring variations of Polycomb Repressive Complex 1 (PRC1) comprise a core assembly of Polycomb group proteins and additional factors that include, surprisingly, Autism Susceptibility Candidate 2 (AUTS2). While AUTS2 is often disrupted in patients with neuronal disorders, the underlying ...
ORGANISM(S): Mus musculus 
2014-12-18 | E-GEOD-60410 | biostudies-arrayexpress
GenomicsGenome-wide maps of chromatin state in medium spiny neurons in the striatum of adult mice
Normal brain function critically depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions. The fidelity of neuronal specification is contingent upon the robustness of the transcriptional program that supports the neuron ty...
ORGANISM(S): Mus musculus 
2016-07-29 | E-GEOD-84244 | biostudies-arrayexpress
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